Findings

What do systematic reviews say?

4,411 questions · 5,986 findings · 226 reviews · Oral Health

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No studies found 1,305 · 21.8%GRADE not reported 2,988 · 49.9%Very low 1,030 · 17.2%Low 476 · 8%Moderate 156 · 2.6%High 31 · 0.5%

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Fluoride varnish vs placebo or no treatment

Caries increment on permanent whole teeth (D(M)FT), prevented fraction · Children and adolescents aged 16 years or less

1 finding from 1 review

Fluoride varnishes for preventing dental caries in children and adolescents 2013 · Cochrane All outcomes
At least 1 year
PF 0.44 [0.11, 0.76]
5 studies
GRADE not reported

Pre-radiotherapy extraction of diseased molar teeth vs Conservative treatment (restoration of the teeth and leaving them in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

Overall survival · Patients diagnosed with head and neck cancer planned to undergo any type of radiotherapy (external beam, intensity modulated,…

The review found no eligible studies for this question.

1 finding from 1 review

Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

Intraoral distalising appliance vs Another (different) intraoral distalising appliance

Movement of upper first molars (mm) · Children and adolescents (aged 16 years or less at the start of treatment) undergoing orthodontic treatment to distalise upper first…

1 finding from 1 review

Orthodontic treatment for distalising upper first molars in children and adolescents 2013 · Cochrane All outcomes
SoF table 3 (intraoral vs other intraoral appliance). Assumed risk "Not estimated"; Corresponding risk "Not estimated"; Relative effect "Meta-analysis not appropriate". Quality: very low. Comment: "No pooled estimate…
3 studies · 93 participants
Very low

Immediate loading vs Early loading

Implant failure · Patients who are having osseointegrated root-form dental implants

Immediate loading showed no clear difference in implant failure compared with early loading; GRADE not reported.

1 finding from 1 review

Interventions for replacing missing teeth: different times for loading dental implants 2013 · Cochrane All outcomes
1 year
RR 0.65 [0.26, 1.64]
5 studies
GRADE not reported

Pre-radiotherapy extraction of healthy molar teeth vs Conservative treatment (leaving the teeth in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

Delay in start of radiation treatment · Patients diagnosed with head and neck cancer planned to undergo any type of radiotherapy (external beam, intensity modulated,…

The review found no eligible studies for this question.

1 finding from 1 review

Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

Acupuncture vs sham

Patient satisfaction with treatment · Adults with dry mouth due to radiotherapy (head and neck cancer) or Sjogren's Syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the management of dry mouth: non‐pharmacological interventions 2013 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

Locking plate vs 2 mm non-locking titanium plates

Average pain scores (0-100 VAS) · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement

1 finding from 1 review

Interventions for the management of mandibular fractures 2013 · Cochrane All outcomes
Agarwal 2011 reported a significant decrease in VAS pain from week 1 to the 3-month follow-up, with no difference between groups at the follow-up visits, but presented no supporting data.
1 study
GRADE not reported

Immediate mobilization vs 2 weeks delayed mobilization (IMF)

Average pain scores (0-100 VAS) · Adults with mandibular fractures excluding condyles (fixed with 2 mm titanium miniplates)

1 finding from 1 review

Interventions for the management of mandibular fractures 2013 · Cochrane All outcomes
Pain (scale 1 to 10) was minor in both groups with no significant differences (Table 4): 6 weeks 1.55 vs 1.20; 3 months 1.00 vs 2.64; 6 months 1.30 vs 2.71 (immediate release vs IMF). 95% confidence interval not…
1 study
GRADE not reported

Powered toothbrush (any mode of action) vs Manual toothbrush

Stimulated whole saliva (SWS) · Adults with medication-related dry mouth

Powered toothbrush showed no clear difference in stimulated whole saliva (SWS) compared with manual toothbrush; GRADE not reported.

1 finding from 1 review

Interventions for the management of dry mouth: non‐pharmacological interventions 2013 · Cochrane All outcomes
5 minutes after brushing
MD -0.13 [-1.92, 1.66]
1 study
GRADE not reported

Primary school-based behavioural intervention (both oral hygiene and dietary components) vs No treatment (or delayed treatment)

Frequency of toothbrushing · Children aged 4 to 12 years attending primary school

1 finding from 1 review

Primary school‐based behavioural interventions for preventing caries 2013 · Cochrane All outcomes
Worthington 2001 reported children's brushing frequency: almost all children (99%) at baseline reported twice daily brushing, and this level was maintained across all groups throughout the intervention (in baseline…
1 study
GRADE not reported

Fluoride varnish vs placebo or no treatment

Caries increment on permanent tooth surfaces (D(M)FS), prevented fraction · Children and adolescents aged 16 years or less

1 finding from 1 review

Fluoride varnishes for preventing dental caries in children and adolescents 2013 · Cochrane All outcomes
At least 1 year
PF 0.43 [0.30, 0.57]
13 studies · 6478 participants
Moderate

Locking plate vs 2 mm non-locking titanium plates

Drop-out rate due to protocol deviation · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement

1 finding from 1 review

Interventions for the management of mandibular fractures 2013 · Cochrane All outcomes
Early premature removal of IMF (from hours up to 2 weeks) was reported in 13 of the 90 participants analysed (Collins 2004); participants released their own IMF or reported that "the wires fell off".
1 study · 90 participants
GRADE not reported

Intraoral distalising appliance vs Headgear (extraoral appliance)

Overjet · Children and adolescents (aged 16 years or less at the start of treatment) undergoing orthodontic treatment to distalise upper first…

Intraoral distalising appliance may leads to higher change in overjet (mm) compared with headgear (extraoral appliance) (low certainty).

1 finding from 1 review

Orthodontic treatment for distalising upper first molars in children and adolescents 2013 · Cochrane All outcomes
MD 1.64 [1.26, 2.02]
2 studies · 70 participants
Low

2 mm titanium plates vs 2.5 mm bioresorbable plates

Post-operative pain (residual pain, any severity) · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement

2 mm titanium plates showed no clear difference in post-operative pain (residual pain, any severity) compared with 2.5 mm bioresorbable plates; GRADE not reported.

1 finding from 1 review

Interventions for the management of mandibular fractures 2013 · Cochrane All outcomes
1 month
RR 1.26 [0.57, 2.82]
1 study · 40 participants
GRADE not reported

Any intervention to manage relapse: fixed options (labial braces, lingual braces, fixed lingual wire) or removable options (Hawley's retainer with spring elastomeric module, Bloore removable aligner, other Hawley's retainer modifications, Invisalign, Clearstep) vs no intervention or another intervention

Aesthetics · Participants who previously underwent orthodontic treatment, with subsequent crowding (relapse) of the lower front teeth (lower incisors…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for managing relapse of the lower front teeth after orthodontic treatment 2013 · Cochrane All outcomes
No RCTs met the inclusion criteria for this review. After deduplication, the electronic searching identified 527 publications; after reviewing the titles and abstracts, none focused on interventions to correct the…
0 studies
No studies found

Intraoral distalising appliance vs Headgear (extraoral appliance)

Number of visits to complete treatment · Children and adolescents (aged 16 years or less at the start of treatment) undergoing orthodontic treatment to distalise upper first…

The review found no eligible studies for this question.

1 finding from 1 review

Orthodontic treatment for distalising upper first molars in children and adolescents 2013 · Cochrane All outcomes
Number of attendances required to complete treatment was not reported by these studies.
0 studies
No studies found

Pre-radiotherapy extraction of healthy molar teeth vs Conservative treatment (leaving the teeth in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

Development of post-radiotherapy dental complications (caries, fractured teeth, periapical infection, periodontal disease, osteoradionecrosis) · Patients diagnosed with head and neck cancer planned to undergo any type of radiotherapy (external beam, intensity modulated,…

The review found no eligible studies for this question.

1 finding from 1 review

Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

Zygomatic implants for retaining a maxillary obturator vs Non-implant retained obturators, local and regional flaps, or microvascular free flaps

Outcome not reported · Patients requiring maxillary reconstruction after partial or total maxillectomy (cancer patients)

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for replacing missing teeth: dental implants in zygomatic bone for the rehabilitation of the severely… 2013 · Cochrane All outcomes
At least 1 year in function
Results (Effects of interventions): we could not identify any eligible randomised controlled trials (RCTs).
0 studies
No studies found

Electrostimulation (device) vs Placebo (sham/placebo device)

Unstimulated whole saliva (UWS) · Adults with dry mouth due to Sjogren's Syndrome

It is very uncertain whether electrostimulation (device) changes unstimulated whole saliva (UWS) compared with placebo (sham/placebo device) (very low certainty).

1 finding from 1 review

Interventions for the management of dry mouth: non‐pharmacological interventions 2013 · Cochrane All outcomes
End of treatment (4 weeks)
MD 0.02 [-0.12, 0.16]
1 study · 24 participants
Very low

Root canal medicaments vs No medicaments, placebo, or a different type of medicament

Outcome not reported · Patients (mainly children and young adults) with a history of dental trauma and a diagnosis of luxation (intrusion, extrusion, or lateral…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for treating traumatised permanent front teeth: luxated (dislodged) teeth 2013 · Cochrane All outcomes
Minimum 12 months follow-up
Types of root canal medicaments: this was compared with no medicaments, placebo and different types of medicaments. Main results: No randomised or quasi-randomised controlled trials were found; no study was included in…
0 studies
No studies found