Findings

What do systematic reviews say?

4,720 questions · 15,377 findings · 900 reviews

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No studies found 3,865 · 25.1%GRADE not reported 2,291 · 14.9%Very low 3,875 · 25.2%Low 3,287 · 21.4%Moderate 1,681 · 10.9%High 378 · 2.5%

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Topical mydriatics vs intracameral mydriatics

Intraoperative surgical time—total intraoperative time (min) · patients undergoing cataract surgery

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 817 participants
Low

Topical mydriatics vs intracameral mydriatics

Total time it took for the surgeon to perform phacoemulsification (seconds) · patients undergoing cataract surgery

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 48 participants
Very low

Topical mydriatics vs intracameral mydriatics

AE: participant‐reported ocular discomfort—week 1 · patients undergoing cataract surgery

It is very uncertain whether topical mydriatics changes AE: participant‐reported ocular discomfort—week 1 compared with intracameral mydriatics (very low certainty).

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
RR 10.57 [1.37, 81.34]
1 study · 555 participants
Very low

Topical mydriatics vs intracameral mydriatics

AE: participant‐reported ocular discomfort—month 1 · patients undergoing cataract surgery

Topical mydriatics probably leads to higher AE: participant‐reported ocular discomfort—month 1 compared with intracameral mydriatics (moderate certainty).

1 finding from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
RR 2.51 [1.36, 4.65]
1 study · 543 participants
Moderate

Topical mydriatics vs intracameral mydriatics

AE: posterior capsule rupture · patients undergoing cataract surgery

Topical mydriatics showed no clear difference in AE: posterior capsule rupture compared with intracameral mydriatics (low certainty).

2 findings from 1 review

Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
RR 0.32 [0.01, 7.83]
1 study · 555 participants
Low
Pharmacologic interventions for mydriasis in cataract surgery 2021 · Cochrane Headline outcomes only
RR 0.32 [0.01, 7.83]
1 study · 555 participants
Low

Psychological interventions vs usual care

Proportion of wounds healed · adults with diabetes with current or previous foot ulceration

It is very uncertain whether psychological intervention changes proportion of wounds completely healed at 3 months compared with standard care (very low certainty).

2 findings from 1 review

Psychological interventions for treating foot ulcers, and preventing their recurrence, in people with diabetes 2021 · Cochrane Headline outcomes only
RR 6.25
2 studies · 76 participants
Very low
Psychological interventions for treating foot ulcers, and preventing their recurrence, in people with diabetes 2021 · Cochrane Headline outcomes only
RR 0.59
2 studies · 76 participants
Very low

Psychological interventions vs Other Psychological Interventions

Number of foot ulcer recurrences · adults with diabetes with current or previous foot ulceration

The review found no eligible studies for this question.

1 finding from 1 review

Psychological interventions for treating foot ulcers, and preventing their recurrence, in people with diabetes 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Psychological interventions vs usual care

Time to complete healing · adults with diabetes with current or previous foot ulceration

The review found no eligible studies for this question.

1 finding from 1 review

Psychological interventions for treating foot ulcers, and preventing their recurrence, in people with diabetes 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Psychological interventions vs usual care

Time to recurrence · adults with diabetes with current or previous foot ulceration

The review found no eligible studies for this question.

1 finding from 1 review

Psychological interventions for treating foot ulcers, and preventing their recurrence, in people with diabetes 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Psychological interventions vs usual care

Number of foot ulcer recurrences · adults with diabetes with current or previous foot ulceration

It is very uncertain whether psychological intervention changes number of foot ulcer recurrences at 1 year compared with standard care (very low certainty).

2 findings from 1 review

Psychological interventions for treating foot ulcers, and preventing their recurrence, in people with diabetes 2021 · Cochrane Headline outcomes only
RR 0.67
2 studies · 54 participants
Very low
Psychological interventions for treating foot ulcers, and preventing their recurrence, in people with diabetes 2021 · Cochrane Headline outcomes only
RR 0.63
2 studies · 54 participants
Very low

Psychological interventions vs Other Psychological Interventions

Proportion of wounds healed · adults with diabetes with current or previous foot ulceration

It is very uncertain whether psychological intervention changes proportion of wounds completely healed at 3 months compared with another psychological intervention (very low certainty).

1 finding from 1 review

Psychological interventions for treating foot ulcers, and preventing their recurrence, in people with diabetes 2021 · Cochrane Headline outcomes only
RR 2.33
1 study · 16 participants
Very low

Psychological interventions vs Other Psychological Interventions

Time to complete healing · adults with diabetes with current or previous foot ulceration

1 finding from 1 review

Psychological interventions for treating foot ulcers, and preventing their recurrence, in people with diabetes 2021 · Cochrane Headline outcomes only
no estimate extracted
2001 participants
GRADE not reported

Psychological interventions vs Other Psychological Interventions

Time to foot ulcer recurrence · adults with diabetes with current or previous foot ulceration

The review found no eligible studies for this question.

1 finding from 1 review

Psychological interventions for treating foot ulcers, and preventing their recurrence, in people with diabetes 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Eculizumab vs placebo or alternative treatment

Death · children and adults with aHUS

1 finding from 1 review

Interventions for atypical haemolytic uraemic syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
100 participants
Very low

Ravulizumab vs placebo or alternative treatment

Remission · adults with aHUS

1 finding from 1 review

Interventions for atypical haemolytic uraemic syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
56 participants
Very low

Ravulizumab vs placebo or alternative treatment

Change in eGFR · adults with aHUS

1 finding from 1 review

Interventions for atypical haemolytic uraemic syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
56 participants
Very low

Ravulizumab vs placebo or alternative treatment

Health‐related quality of life · adults with aHUS

1 finding from 1 review

Interventions for atypical haemolytic uraemic syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
44 participants
Very low

Ravulizumab vs placebo or alternative treatment

Adverse events · adults with aHUS

1 finding from 1 review

Interventions for atypical haemolytic uraemic syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
58 participants
Very low

Ravulizumab vs placebo or alternative treatment

Meningococcal infection · adults with aHUS

1 finding from 1 review

Interventions for atypical haemolytic uraemic syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
58 participants
Very low

Eculizumab vs placebo or alternative treatment

Requirement for KRT · children and adults with aHUS

1 finding from 1 review

Interventions for atypical haemolytic uraemic syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
100 participants
Very low