Findings

What do systematic reviews say?

4,345 questions · 4,525 findings · 483 reviews

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No studies found 1,024 · 22.6%GRADE not reported 388 · 8.6%Very low 1,172 · 25.9%Low 1,227 · 27.1%Moderate 576 · 12.7%High 138 · 3%

Open surgical excision vs eccentric exercises

Knee pain (short term) VAS scale: 0 to 10; higher score = worse pain. · adult participants with patellar tendinopathy

1 finding from 1 review

Surgery for patellar tendinopathy (jumper’s knee) 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Low

Open surgical excision vs eccentric exercises

Functional outcomes · adult participants with patellar tendinopathy

1 finding from 1 review

Surgery for patellar tendinopathy (jumper’s knee) 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Low

Open surgical excision vs eccentric exercises

Participant global assessment of success (People who perceived their pain as none) · adult participants with patellar tendinopathy

Open surgical excision showed no clear difference in participant global assessment of success (People who perceived their… compared with eccentric exercises (low certainty).

1 finding from 1 review

Surgery for patellar tendinopathy (jumper’s knee) 2019 · Cochrane Headline outcomes only
RR 0.71 [0.27, 1.88]
1 study · 40 participants
Low

Open surgical excision vs eccentric exercises

Quality of life · adult participants with patellar tendinopathy

The review found no eligible studies for this question.

1 finding from 1 review

Surgery for patellar tendinopathy (jumper’s knee) 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Open surgical excision vs eccentric exercises

Leaving the study early · adult participants with patellar tendinopathy

1 finding from 1 review

Surgery for patellar tendinopathy (jumper’s knee) 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Low

Open surgical excision vs eccentric exercises

Adverse event · adult participants with patellar tendinopathy

1 finding from 1 review

Surgery for patellar tendinopathy (jumper’s knee) 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Very low

Open surgical excision vs eccentric exercises

Tendon rupture · adult participants with patellar tendinopathy

The review found no eligible studies for this question.

1 finding from 1 review

Surgery for patellar tendinopathy (jumper’s knee) 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antifibrinolytic agents (tranexamic acid (TXA) or epsilon aminocaproic acid (EACA)) vs Placebo, no intervention, or usual care

Outcome not reported · People on continuous direct oral anticoagulant (DOAC) treatment undergoing oral or dental procedures

The review found no eligible studies for this question.

1 finding from 1 review

Antifibrinolytic therapy for preventing oral bleeding in people on anticoagulants undergoing minor oral surgery or… 2018 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

Laparoscopic vs open appendectomy

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · patients with suspected appendicitis

3 findings from 1 review

Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
no estimate extracted
20 studies · 2421 participants
Low
Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 613 participants
Low
Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Laparoscopic vs open appendectomy

Length of hospital stay · patients with suspected appendicitis

4 findings from 1 review

Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 316 participants
Low
Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
no estimate extracted
17 studies · 1977 participants
Low
Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 140 participants
Very low

Show 1 more finding

Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
no estimate extracted
46 studies · 5127 participants
Low

Laparoscopic vs open appendectomy

Return to normal activities (days) · patients with suspected appendicitis

2 findings from 1 review

Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 383 participants
Moderate
Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
no estimate extracted
17 studies · 1653 participants
Low

Laparoscopic vs open appendectomy

Quality of life · patients with suspected appendicitis

The review found no eligible studies for this question.

2 findings from 1 review

Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found
Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Laparoscopic vs open appendectomy

Wound infection · patients with suspected appendicitis

Subgroup analysis (publication date) ‐ Laparoscopic probably leads to lower wound infections compared with open appendectomy (moderate certainty).

3 findings from 1 review

Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
Peto OR 0.37 [0.27, 0.51]
19 studies · 2217 participants
Moderate
Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
Peto OR 0.42 [0.35, 0.51]
63 studies · 7612 participants
Moderate
Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
Peto OR 0.27 [0.14, 0.52]
5 studies · 783 participants
Moderate

Laparoscopic vs open appendectomy

Intra‐abdominal abscess · patients with suspected appendicitis

Subgroup analysis (publication date) ‐ Laparoscopic showed no clear difference in intra‐abdominal abscesses compared with open appendectomy (low certainty).

4 findings from 1 review

Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
Peto OR 0.82 [0.44, 1.51]
11 studies · 1466 participants
Low
Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
Peto OR 0.45 [0.19, 1.07]
4 studies · 723 participants
Low
Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
Peto OR 1.65 [1.12, 2.43]
53 studies · 6677 participants
Moderate

Show 1 more finding

Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
Peto OR 0.54 [0.24, 1.22]
9 studies · 1185 participants
Low

Laparoscopic vs open appendectomy

Return to normal activity · patients with suspected appendicitis

2 findings from 1 review

Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 380 participants
Very low
Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 383 participants
Moderate

Laparoscopic vs open appendectomy

Quality of life Scale used: Gastro‐intestinal Quality of Life Index · patients with suspected appendicitis

1 finding from 1 review

Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
no estimate extracted
2009 participants
Low

Laparoscopic vs open appendectomy

Quality of life Scale used: 1) Gastro‐intestinal Quality of Life Index 2) SF‐36 questionnaire · patients with suspected appendicitis

1 finding from 1 review

Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
2
2009 participants
Low

Laparoscopic vs open appendectomy

Pain (unpleasantness/intensity/palpation) · patients with suspected appendicitis

1 finding from 1 review

Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 61 participants
Low

Laparoscopic vs open appendectomy

Surgical complications ‐ wound infection · patients with suspected appendicitis

Laparoscopic probably leads to lower wound infections (rate) compared with open appendectomy (moderate certainty).

1 finding from 1 review

Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
Peto OR 0.25 [0.15, 0.42]
10 studies · 1245 participants
Moderate

Intervention not reported

Limb salvage at 30 days · patients seeking treatment for initial management of acute limb ischaemia

The intervention showed no clear difference in limb salvage at 30 days (low certainty).

1 finding from 1 review

Surgery versus thrombolysis for initial management of acute limb ischaemia 2018 · Cochrane Headline outcomes only
OR 1.02 [0.41, 2.55]
4 studies · 636 participants
Low