Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,345 questions · 4,525 findings · 483 reviews

No studies found 1,024 · 22.6%GRADE not reported 388 · 8.6%Very low 1,172 · 25.9%Low 1,227 · 27.1%Moderate 576 · 12.7%High 138 · 3%

Intervention not reported

Proportion free from seizures (Engel Class 1) at 2 years · adults and children with drug‐resistant epilepsy suitable for surgical intervention

The intervention showed no clear difference in proportion free from seizures (Engel Class 1) at 2 years (moderate certainty).

1 finding from 1 review
  • Surgery for epilepsy 2019 · Cochrane Headline outcomes only
    RR 1.22 [0.85, 1.76]
    1 study · 60 participants
    Moderate

Intervention not reported

Proportion free from all seizures (including auras, ILAE 1a) at 1 year · adults and children with drug‐resistant epilepsy suitable for surgical intervention

The intervention showed no clear difference in proportion free from all seizures (including auras, ILAE 1a) at 1 year (low certainty).

1 finding from 1 review
  • Surgery for epilepsy 2019 · Cochrane Headline outcomes only
    RR 0.92 [0.59, 1.46]
    1 study · 47 participants
    Low

Intervention not reported

Proportion free from all seizures (including auras) at 1 year · adults and children with drug‐resistant epilepsy suitable for surgical intervention

The intervention may leads to higher proportion free from all seizures (including auras) at 1 year (low certainty).

1 finding from 1 review
  • Surgery for epilepsy 2019 · Cochrane Headline outcomes only
    RR 1.82 [1.12, 2.93]
    1 study · 70 participants
    Low

Intraoperative neuromonitoring vs visual nerve identification only during thyroidectomy

Adverse events other than RILN palsy (participants) Definition: transient hypoparathyroidism

It is very uncertain whether intraoperative neuromonitoring changes adverse events other than RILN palsy (participants) Definition:… compared with visual nerve identification only during thyroidectomy (very low certainty).

1 finding from 1 review

IStent in combination with phacoemulsification vs phacoemulsification alone

Proportion of participants who were drop‐free · open‐angle glaucoma

It is very uncertain whether IStent in combination with phacoemulsification changes proportion of participants who were drop‐free compared with phacoemulsification alone (very low certainty).

1 finding from 1 review