Findings

What do systematic reviews say?

4,410 questions · 8,901 findings · 1,091 reviews

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No studies found 1,687 · 19%GRADE not reported 1,469 · 16.5%Very low 1,969 · 22.1%Low 2,060 · 23.1%Moderate 1,302 · 14.6%High 414 · 4.7%

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Intervention not reported

Oliguria (urine output < 1 mL/kg/hour) · preterm infants with patent ductus arteriosus

The intervention probably leads to lower oliguria (urine output < 1 mL/kg/hour) (moderate certainty).

1 finding from 1 review

Ibuprofen for the treatment of patent ductus arteriosus in preterm or low birth weight (or both) infants 2020 · Cochrane Headline outcomes only
RR 0.28 [0.14, 0.54]
6 studies · 576 participants
Moderate

Intervention not reported

Serum/plasma creatinine levels (μmol/L) · preterm infants with patent ductus arteriosus

The intervention showed no clear difference in serum/plasma creatinine levels (μmol/L) (low certainty).

1 finding from 1 review

Ibuprofen for the treatment of patent ductus arteriosus in preterm or low birth weight (or both) infants 2020 · Cochrane Headline outcomes only
no estimate extracted
11 studies · 918 participants
Low

Intervention not reported

Failure to close a patent ductus arteriosus (PDA) (after 3 doses) · preterm infants with patent ductus arteriosus

The intervention showed no clear difference in failure to close a patent ductus arteriosus (PDA) (after 3 doses) (low certainty).

1 finding from 1 review

Ibuprofen for the treatment of patent ductus arteriosus in preterm or low birth weight (or both) infants 2020 · Cochrane Headline outcomes only
RR 0.96 [0.73, 1.27]
8 studies · 272 participants
Low

Intervention not reported

Undercorrected vs fully corrected spectacles · children with myopia (nearsightedness)

1 finding from 1 review

Interventions to slow progression of myopia in children 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 142 participants
Low

Intervention not reported

Systemic 7‐methylxanthine vs placebo · children with myopia (nearsightedness)

1 finding from 1 review

Interventions to slow progression of myopia in children 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 77 participants
Moderate

Intervention not reported

Timolol drops vs no drops · children with myopia (nearsightedness)

1 finding from 1 review

Interventions to slow progression of myopia in children 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 95 participants
Low

Intervention not reported

Atropine plus multifocal spectacles vs placebo plus SVLs · children with myopia (nearsightedness)

1 finding from 1 review

Interventions to slow progression of myopia in children 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 191 participants
Moderate

Intervention not reported

Atropine plus bifocal spectacles vs cyclopentolate plus SVLs · children with myopia (nearsightedness)

1 finding from 1 review

Interventions to slow progression of myopia in children 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 64 participants
Moderate

Intervention not reported

Bifocal spectacles vs SVLs with timolol drops · children with myopia (nearsightedness)

1 finding from 1 review

Interventions to slow progression of myopia in children 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 97 participants
Moderate

Intervention not reported

Tropicamide plus bifocal spectacles vs SVLs · children with myopia (nearsightedness)

1 finding from 1 review

Interventions to slow progression of myopia in children 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
GRADE not reported

Intervention not reported

Comparison (intervention vs comparator) · children with myopia (nearsightedness)

The review found no eligible studies for this question.

1 finding from 1 review

Interventions to slow progression of myopia in children 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Adverse effects · children with myopia (nearsightedness)

The review found no eligible studies for this question.

1 finding from 1 review

Interventions to slow progression of myopia in children 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Multifocal vs single vision lens spectacles · children with myopia (nearsightedness)

1 finding from 1 review

Interventions to slow progression of myopia in children 2020 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 1463 participants
Moderate

Intervention not reported

Peripheral plus spectacles vs single vision lens spectacles · children with myopia (nearsightedness)

1 finding from 1 review

Interventions to slow progression of myopia in children 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 597 participants
Low

Intervention not reported

Bifocal vs single vision soft contact lenses · children with myopia (nearsightedness)

1 finding from 1 review

Interventions to slow progression of myopia in children 2020 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 300 participants
Low

Intervention not reported

Rigid gas permeable contact lenses vs spectacles or soft contact lenses · children with myopia (nearsightedness)

1 finding from 1 review

Interventions to slow progression of myopia in children 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 420 participants
Very low

Intervention not reported

Orthokeratology contact lenses vs single vision lenses · children with myopia (nearsightedness)

The review found no eligible studies for this question.

1 finding from 1 review

Interventions to slow progression of myopia in children 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Spherical aberration soft contact lenses vs single vision soft contact lenses · children with myopia (nearsightedness)

1 finding from 1 review

Interventions to slow progression of myopia in children 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 209 participants
Low

Intervention not reported

Antimuscarinic agents vs placebo · children with myopia (nearsightedness)

1 finding from 1 review

Interventions to slow progression of myopia in children 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 629 participants
Moderate

Intervention not reported

Atropine vs tropicamide · children with myopia (nearsightedness)

1 finding from 1 review

Interventions to slow progression of myopia in children 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 196 participants
Low