Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,756 questions · 11,779 findings · 747 reviews · Headline outcomes only

No studies found 3,205 · 27.2%GRADE not reported 628 · 5.3%Very low 3,261 · 27.7%Low 2,913 · 24.7%Moderate 1,453 · 12.3%High 319 · 2.7%

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New‐generation antidepressants vs placebo

Repetition of SH at post‐intervention · self‐harm in adults

It is very uncertain whether newer generation antidepressants (NGAs) changes repetition of SH by post‐intervention (NGA class)№ of participants:… compared with placebo (very low certainty).

3 findings from 1 review

Mood stabilisers vs placebo

Repetition of SH at post‐intervention · self‐harm in adults

It is very uncertain whether mood stabilisers, including antiepileptics and lithium changes repetition of SH by post‐intervention№ of participants: 167(1 RCT) compared with placebo (very low certainty).

1 finding from 1 review

Intervention not reported

Change in BCVA from baseline to 6‐month · People with lamellar macular holes
1 finding from 1 review

Intervention not reported

Change in metamorphopsia from baseline to 6‐month · People with lamellar macular holes

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Change in anatomical outcomes (CRT) from baseline to 6‐month · People with lamellar macular holes
1 finding from 1 review

Intervention not reported

Vision‐related quality of life · People with lamellar macular holes

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Adverse outcomes · People with lamellar macular holes

The review found no eligible studies for this question.

1 finding from 1 review

Mindfulness vs no treatment or waiting list

Mental health and well‐being: stress or stress perceptionMeasured by: investigators measured stress or stress perception using different instruments; lower scores mean lower stress or stress perception Timing of outcome assessment: post‐intervention
1 finding from 1 review