What do systematic reviews say?

Any O‐BCS vs mastectomy plus reconstruction

• Oncoplastic breast‐conserving surgery for women with primary breast cancer 2021 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Any O‐BCS vs mastectomy plus reconstruction

It is very uncertain whether any O‐BCS changes disease‐free survival compared with mastectomy plus reconstruction (very low certainty).

• Oncoplastic breast‐conserving surgery for women with primary breast cancer 2021 · Cochrane Headline outcomes only
  HR 0.45 [0.09, 2.22]
  1 study · 317 participants
  Very low

Any O‐BCS vs mastectomy plus reconstruction

• Oncoplastic breast‐conserving surgery for women with primary breast cancer 2021 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Any O‐BCS vs mastectomy plus reconstruction

It is very uncertain whether any O‐BCS changes complications compared with mastectomy plus reconstruction (very low certainty).

• Oncoplastic breast‐conserving surgery for women with primary breast cancer 2021 · Cochrane Headline outcomes only
  RR 0.49 [0.45, 0.54]
  5 studies · 4973 participants
  Very low

Any O‐BCS vs S‐BCS

Any O‐BCS showed no clear difference in local recurrence rates (up to 5 years) compared with S‐BCS (low certainty).

• Oncoplastic breast‐conserving surgery for women with primary breast cancer 2021 · Cochrane Headline outcomes only
  HR 1.33 [0.96, 1.83]
  4 studies · 2443 participants
  Low

Any O‐BCS vs mastectomy plus reconstruction

• Oncoplastic breast‐conserving surgery for women with primary breast cancer 2021 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Any O‐BCS vs mastectomy plus reconstruction

• Oncoplastic breast‐conserving surgery for women with primary breast cancer 2021 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 3 participants
  GRADE not reported

Any O‐BCS vs S‐BCS

Any O‐BCS showed no clear difference in disease‐free survival (up to 5 years) compared with S‐BCS (low certainty).

• Oncoplastic breast‐conserving surgery for women with primary breast cancer 2021 · Cochrane Headline outcomes only
  HR 1.06 [0.89, 1.26]
  7 studies · 5532 participants
  Low

Any O‐BCS vs S‐BCS

It is very uncertain whether any O‐BCS changes re‐excision rate: total re‐excisions compared with S‐BCS (very low certainty).

• Oncoplastic breast‐conserving surgery for women with primary breast cancer 2021 · Cochrane Headline outcomes only
  RR 0.76 [0.69, 0.85]
  38 studies · 13341 participants
  Very low

Any O‐BCS vs S‐BCS

It is very uncertain whether any O‐BCS changes complications compared with S‐BCS (very low certainty).

• Oncoplastic breast‐conserving surgery for women with primary breast cancer 2021 · Cochrane Headline outcomes only
  RR 1.19 [1.1, 1.27]
  20 studies · 118005 participants
  Very low

Any O‐BCS vs S‐BCS

Any O‐BCS may leads to higher recall rate compared with S‐BCS (low certainty).

• Oncoplastic breast‐conserving surgery for women with primary breast cancer 2021 · Cochrane Headline outcomes only
  RR 2.39 [1.67, 3.42]
  6 studies · 715 participants
  Low

Any O‐BCS vs S‐BCS

• Oncoplastic breast‐conserving surgery for women with primary breast cancer 2021 · Cochrane Headline outcomes only
  no estimate extracted
  24 studies · 5665 participants
  Very low

Any O‐BCS vs mastectomy

It is very uncertain whether any O‐BCS changes local recurrence‐free survival (up to 5 years) compared with mastectomy (very low certainty).

• Oncoplastic breast‐conserving surgery for women with primary breast cancer 2021 · Cochrane Headline outcomes only
  HR 0.55 [0.34, 0.91]
  2 studies · 4713 participants
  Very low

Any O‐BCS vs mastectomy

• Oncoplastic breast‐conserving surgery for women with primary breast cancer 2021 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Early open repair vs ultrasound surveillance

Early open repair leads to lower mortality ( compared with ultrasound surveillance (high certainty).

• Surgery for small asymptomatic abdominal aortic aneurysms 2020 · Cochrane Headline outcomes only
  HR 0.99
  2 studies · 2226 participants
  High

Early open repair vs ultrasound surveillance

Early open repair showed no clear difference in costs (per participant) ( compared with ultrasound surveillance (moderate certainty).

• Surgery for small asymptomatic abdominal aortic aneurysms 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 1090 participants
  Moderate

Early open repair vs ultrasound surveillance

• Surgery for small asymptomatic abdominal aortic aneurysms 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 2226 participants
  GRADE not reported

Early open repair vs ultrasound surveillance

• Surgery for small asymptomatic abdominal aortic aneurysms 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 2226 participants
  GRADE not reported

Early endovascular repair vs ultrasound surveillance

Early endovascular repair showed no clear difference in mortality ( compared with ultrasound surveillance (low certainty).

• Surgery for small asymptomatic abdominal aortic aneurysms 2020 · Cochrane Headline outcomes only
  RR 1.92 [0.73, 5.06]
  2 studies · 846 participants
  Low

Early endovascular repair vs ultrasound surveillance

Early endovascular repair showed no clear difference in costs ( compared with ultrasound surveillance (low certainty).

• Surgery for small asymptomatic abdominal aortic aneurysms 2020 · Cochrane Headline outcomes only
  MD 27
  1 study · 614 participants
  Low
• Surgery for small asymptomatic abdominal aortic aneurysms 2020 · Cochrane Headline outcomes only
  MD 2557
  1 study · 614 participants
  Low