Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,678 questions · 4,859 findings · 283 reviews

No studies found 1,225 · 25.2%GRADE not reported 215 · 4.4%Very low 1,241 · 25.5%Low 1,210 · 24.9%Moderate 776 · 16%High 192 · 4%

Summary of findings table ‐ Exercise plus usual pharmacological care vs placebo + standard care

Withdrawals due to any reason · systemic lupus erythematosus

It is very uncertain whether summary of findings table ‐ Exercise plus usual pharmacological care changes withdrawals due to any reason compared with placebo plus usual pharmacological care (very low certainty).

1 finding from 1 review

Summary of findings ‐ structured telephone support or telemonitoring vs usual care

All‐cause mortality: Structured telephone support versus usual care · patients with heart failure

Summary of findings ‐ structured telephone support or telemonitoring probably leads to lower all‐cause mortality: Structured telephone support versus usual care compared with usual care ‐ all‐cause mortality (moderate certainty).

1 finding from 1 review

Summary of findings ‐ structured telephone support or telemonitoring vs usual care

Death (all causes) · patients with heart failure

Summary of findings ‐ structured telephone support or telemonitoring probably leads to lower all‐cause mortality: Telemonitoring versus usual care compared with usual care ‐ all‐cause mortality (moderate certainty).

1 finding from 1 review

Summary of findings ‐ structured telephone support or telemonitoring vs usual care ‐ all‐cause hospitalisation

Hospitalisation (any cause) · patients with heart failure

It is very uncertain whether summary of findings ‐ structured telephone support or telemonitoring changes all‐cause hospitalisation: Structured telephone support verus usual… compared with usual care ‐ all‐cause hospitalisation (very low certainty).

2 findings from 1 review

Summary of findings ‐ structured telephone support or telemonitoring vs usual care

Heart failure hospitalisation (RR) · patients with heart failure

Summary of findings ‐ structured telephone support or telemonitoring probably leads to lower CHF‐related hospitalisation: Structured telephone support versus… compared with usual care ‐ heart failure‐related hospitalisation (moderate certainty).

2 findings from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

Fetal/neonatal/infant · the fetus/neonate/infant

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroid showed no clear difference in A1: Fetal or neonatal or infant death (< 1 year of age) – all… compared with single course (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

Respiratory distress syndrome · the fetus/neonate/infant

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroid leads to lower A5: Respiratory distress syndrome – all fetuses randomised compared with single course (high certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

A7: Severe lung disease – all fetuses randomised · the fetus/neonate/infant

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroid probably leads to lower A7: Severe lung disease – all fetuses randomised compared with single course (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

Chronic lung disease · the fetus/neonate/infant

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroid showed no clear difference in A8: Chronic lung disease – all fetuses randomised compared with single course (high certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

Intraventricular haemorrhage, Papile grade 3/4 · the fetus/neonate/infant

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroid showed no clear difference in A9: Severe intraventricular haemorrhage (grade 3 or 4) – all fetuses… compared with single course (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

Necrotising enterocolitis · the fetus/neonate/infant

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroid showed no clear difference in A11: Necrotising enterocolitis – all fetuses randomised compared with single course (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

A12: Composite of serious outcomes– all fetuses randomised · the fetus/neonate/infant

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroid probably leads to lower A12: Composite of serious outcomes– all fetuses randomised compared with single course (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ High‐dose dexamethasone (12 mg or higher) vs low‐dose dexamethasone (6 mg to 8 mg)

All‐cause mortality up to 30 days · hospitalised individuals with unknown vaccination status and a confirmed diagnosis of symptomatic COVID‐19

Summary of findings table ‐ High‐dose dexamethasone (12 mg or higher) showed no clear difference in all‐cause mortality up to 30 days compared with low‐dose dexamethasone (6 mg to 8 mg) (low certainty).

1 finding from 1 review

Summary of findings table ‐ High‐dose dexamethasone (12 mg or higher) vs low‐dose dexamethasone (6 mg to 8 mg)

All‐cause mortality up to 120 days · hospitalised individuals with unknown vaccination status and a confirmed diagnosis of symptomatic COVID‐19

It is very uncertain whether summary of findings table ‐ High‐dose dexamethasone (12 mg or higher) changes all‐cause mortality up to 120 days compared with low‐dose dexamethasone (6 mg to 8 mg) (very low certainty).

1 finding from 1 review