Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

583 questions · 638 findings · 60 reviews · Infectious Diseases

No studies found 54 · 8.5%GRADE not reported 98 · 15.4%Very low 118 · 18.5%Low 141 · 22.1%Moderate 141 · 22.1%High 86 · 13.5%

Intervention not reported

Mosquito mortality (washed nets) · adults and childen living in malaria‐endemic areas, Anopheles gambiae complex or Anopheles funestus group

It is very uncertain whether the intervention changes mosquito mortality (washed nets) (very low certainty).

1 finding from 1 review

Hydroxychloroquine (HCQ) vs placebo or usual care

Negative PCR for SARS‐CoV‐2 on respiratory samples at day 14 from enrolmentd · adults with mild to severe COVID‐19

Hydroxychloroquine (HCQ) showed no clear difference in negative PCR for SARS‐CoV‐2 on respiratory samples at day 14 from… compared with standard care or placebo (low certainty).

1 finding from 1 review

Hydroxychloroquine (HCQ) vs placebo or usual care

Participants with prolongation of QT‐interval on ECG · adults with mild to severe COVID‐19

It is very uncertain whether hydroxychloroquine (HCQ) changes participants with prolongation of QT‐interval on ECG compared with standard care or placebo (very low certainty).

1 finding from 1 review

Hydroxychloroquine (HCQ) vs placebo

Development of confirmed COVID‐19 at 14 days from enrolment · people who have been exposed to SARS‐CoV‐2

It is very uncertain whether hydroxychloroquine (HCQ) changes development of confirmed COVID‐19 at 14 days from enrolment compared with placebo (very low certainty).

1 finding from 1 review