Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

513 questions · 543 findings · 92 reviews · Headline outcomes only

No studies found 101 · 18.6%GRADE not reported 29 · 5.3%Very low 151 · 27.8%Low 150 · 27.6%Moderate 92 · 16.9%High 20 · 3.7%

Intervention not reported

Physical Function ‐ not measured · patients with big toe joint osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review

Psychological therapy vs Waitlist/Usual Care

Secondary outcome: acceptability of treatment · people with somatoform disorders and medically unexplained physical symptoms

Psychological therapy probably leads to lower acceptability 1 ‐ proportion of participants withdrawing during… compared with usual care or waiting list (moderate certainty).

1 finding from 1 review

Psychological therapy vs Waitlist/Usual Care

Global Impressions scale change item (CGI‐I or similar): no. of responders (acute phase) · people with somatoform disorders and medically unexplained physical symptoms

Psychological therapy may leads to higher treatment response at end of treatment CGI‐improvement/Global… compared with usual care or waiting list (low certainty).

1 finding from 1 review