Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,429 questions · 3,558 findings · 436 reviews

No studies found 660 · 18.5%GRADE not reported 375 · 10.5%Very low 727 · 20.4%Low 887 · 24.9%Moderate 709 · 19.9%High 200 · 5.6%

Pulsed dye laser vs Nd:YAG laser

Lesion count ‐ not measured · Participants with rosacea

The review found no eligible studies for this question.

1 finding from 1 review

Pulsed dye laser vs Nd:YAG laser

Time needed until improvement ‐ not measured · Participants with rosacea

The review found no eligible studies for this question.

1 finding from 1 review

Pulsed dye laser vs Nd:YAG laser

Duration of remission ‐ not measured · Participants with rosacea

The review found no eligible studies for this question.

1 finding from 1 review

Intense pulsed light vs no treatment

Participant global assessment: satisfaction with treatment Questionnaire · participants with hidradenitis suppurativa

Intense pulsed light may leads to higher participant global assessment: satisfaction with treatment… compared with no treatment (low certainty).

1 finding from 1 review

Intense pulsed light vs no treatment

Participant global assessment: satisfaction with treatment ‐ axilla Questionnaire · participants with hidradenitis suppurativa

Intense pulsed light may leads to higher participant global assessment: satisfaction with treatment ‐ axilla… compared with no treatment (low certainty).

1 finding from 1 review

Intense pulsed light vs no treatment

Participant global assessment: satisfaction with treatment ‐ groin Questionnaire · participants with hidradenitis suppurativa

Intense pulsed light showed no clear difference in participant global assessment: satisfaction with treatment ‐ groin… compared with no treatment (low certainty).

1 finding from 1 review

Intense pulsed light vs no treatment

Participant global assessment: satisfaction with treatment ‐ inframammary Questionnaire · participants with hidradenitis suppurativa

Intense pulsed light showed no clear difference in participant global assessment: satisfaction with treatment ‐… compared with no treatment (low certainty).

1 finding from 1 review

Cervical pull headgear vs Minor interceptive procedures (control)

Amount of crowding (lower incisor crowding) at 10 weeks · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

It is very uncertain whether cervical pull headgear changes amount of crowding (lower incisor crowding) at 2 years compared with minor interceptive procedures (control) (very low certainty).

1 finding from 1 review

Cervical pull headgear vs Minor interceptive procedures (control)

Size of the jaws (maxillary and mandibular arch length) · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

Cervical pull headgear led to higher size of the jaws (maxillary and mandibular arch length) compared with minor interceptive procedures (control); GRADE not reported.

1 finding from 1 review

Cervical pull headgear vs Minor interceptive procedures (control)

Position of the incisors (upper incisor inclination) · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

Cervical pull headgear led to higher upper incisors to maxilla at 2 years compared with minor interceptive procedures (control); GRADE not reported.

1 finding from 1 review

Cervical pull headgear vs Minor interceptive procedures (control)

Lower incisors to mandible (relationship of lower front teeth to the mandible) · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

Cervical pull headgear showed no clear difference in lower incisors to mandible at 2 years compared with minor interceptive procedures (control); GRADE not reported.

1 finding from 1 review

Pulse cyclophosphamide vs continuous cyclophosphamide

Recurrence of hyperthyroidism (relapse) [measured by serum thyroid hormone levels above the normal range after withdrawal of methimazole or end of radioiodine treatment] · adults with renal vasculitis

Pulse cyclophosphamide may leads to higher relapse at the end of compared with continuous cyclophosphamide (low certainty).

1 finding from 1 review