Bisphosphonates vs placebo or no intervention
- Bisphosphonates for osteoporosis in primary biliary cirrhosis 2011 · Cochrane Headline outcomes onlyno estimate extracted3 studies · 100 participantsVery low
It is very uncertain whether hormone replacement changes all‐cause mortality compared with placebo or no intervention (very low certainty).
It is very uncertain whether hormone replacement changes fractures compared with placebo or no intervention (very low certainty).
It is very uncertain whether hormone replacement changes adverse events compared with placebo or no intervention (very low certainty).
It is very uncertain whether hormone replacement changes liver‐related morbidity compared with placebo or no intervention (very low certainty).
It is very uncertain whether methionine and supportive treatment changes mortality compared with supportive treatment (very low certainty).
It is very uncertain whether standard intravenous acetylcysteine regimen (20.5 hour) changes hepatotoxicity compared with shorter intravenous acetylcysteine regimen (12 hour) (very low certainty).
Standard intravenous acetylcysteine regimen (20.5 hour) may leads to lower vomiting, retching, or antiemetics from 0‐2 hours compared with shorter intravenous acetylcysteine regimen (12 hour) (low certainty).
Standard intravenous acetylcysteine regimen (20.5 hour) may leads to lower vomiting, retching, or antiemetics 0‐12 hours compared with shorter intravenous acetylcysteine regimen (12 hour) (low certainty).
Standard intravenous acetylcysteine regimen (20.5 hour) may leads to lower anaphylactoid symptoms compared with shorter intravenous acetylcysteine regimen (12 hour) (low certainty).
The review found no eligible studies for this question.
It is very uncertain whether oral changes nausea compared with intravenous acetylcysteine (very low certainty).
It is very uncertain whether oral changes vomiting compared with intravenous acetylcysteine (very low certainty).