Gamma‐globulin vs serum
Mortality due to measles · susceptible children exposed to measles
1 finding from 1 review
- no estimate extracted0 studies · 0 participantsGRADE not reported
Findings
What do systematic reviews say?
374 questions · 393 findings · 47 reviews · Headline outcomes only
No studies found 73 · 18.6%GRADE not reported 16 · 4.1%Very low 164 · 41.7%Low 85 · 21.6%Moderate 36 · 9.2%High 19 · 4.8%
Gamma‐globulin vs serum
Complications due to measles · susceptible children exposed to measles
1 finding from 1 review
- no estimate extracted0 studies · 0 participantsGRADE not reported
TDF+ FTC vs placebo
HIV infection · High‐risk HIV‐uninfected individuals (including serodiscordant couples, men who have sex with men and sex workers)
TDF+ FTC probably leads to lower HIV infection compared with placebo (moderate certainty).
1 finding from 1 review
- Antiretroviral pre‐exposure prophylaxis (PrEP) for preventing HIV in high‐risk individuals 2012 · Cochrane Headline outcomes onlyRR 0.49 [0.28, 0.85]4 studies · 8813 participantsModerate
TDF+ FTC vs placebo
Serious adverse events · High‐risk HIV‐uninfected individuals (including serodiscordant couples, men who have sex with men and sex workers)
TDF+ FTC showed no clear difference in serious adverse events compared with placebo (moderate certainty).
1 finding from 1 review
- Antiretroviral pre‐exposure prophylaxis (PrEP) for preventing HIV in high‐risk individuals 2012 · Cochrane Headline outcomes onlyRR 1 [0.83, 1.19]3 studies · 6862 participantsModerate
TDF vs placebo
HIV infection · High‐risk individuals (including serodiscordant couples, men who have sex with men and sex workers)
TDF probably leads to lower HIV infection compared with placebo (moderate certainty).
1 finding from 1 review
- Antiretroviral pre‐exposure prophylaxis (PrEP) for preventing HIV in high‐risk individuals 2012 · Cochrane Headline outcomes onlyRR 0.33 [0.2, 0.55]2 studies · 4027 participantsModerate
TDF vs placebo
Serious adverse events · High‐risk individuals (including serodiscordant couples, men who have sex with men and sex workers)
TDF showed no clear difference in serious adverse events compared with placebo (moderate certainty).
1 finding from 1 review
- Antiretroviral pre‐exposure prophylaxis (PrEP) for preventing HIV in high‐risk individuals 2012 · Cochrane Headline outcomes onlyRR 1.03 [0.79, 1.33]1 study · 3168 participantsModerate
Blunt needles vs sharp needles
glove perforations per surgeon per operation · surgical staff
Blunt needles leads to lower glove perforations per surgeon per operation compared with sharp needles (high certainty).
1 finding from 1 review
- Blunt versus sharp suture needles for preventing percutaneous exposure incidents in surgical staff 2011 · Cochrane Headline outcomes onlyRR 0.46 [0.38, 0.54]10 studies · 2961 participantsHigh
Intervention not reported
Mortality, all‐cause · patients with diarrhoea in children with HIV infection
The intervention may leads to lower mortality, all‐cause (low certainty).
1 finding from 1 review
- Prevention of diarrhoea in children with HIV infection or exposure to maternal HIV infection 2010 · Cochrane Headline outcomes onlyRR 0.5 [0.31, 0.79]3 studies · 267 participantsLow
Intervention not reported
Mortality, diarrhoea‐specific · patients with diarrhoea in children with HIV infection
It is very uncertain whether the intervention changes mortality, diarrhoea‐specific (very low certainty).
1 finding from 1 review
- Prevention of diarrhoea in children with HIV infection or exposure to maternal HIV infection 2010 · Cochrane Headline outcomes onlyRR 0.26 [0.03, 2.26]2 studies · 829 participantsVery low
Intervention not reported
Hospitalisations for diarrhoea number of episodes per number · patients with diarrhoea in children with HIV infection
The intervention showed no clear difference in hospitalisations for diarrhoea number of episodes per number (low certainty).
1 finding from 1 review
- Prevention of diarrhoea in children with HIV infection or exposure to maternal HIV infection 2010 · Cochrane Headline outcomes onlyRR 0.25 [0.05, 1.15]1 study · 194 participantsLow
Intervention not reported
Incidence acute diarrhoea different measures by history · patients with diarrhoea in children with HIV infection
1 finding from 1 review
- Prevention of diarrhoea in children with HIV infection or exposure to maternal HIV infection 2010 · Cochrane Headline outcomes onlyno estimate extracted3 studies · 267 participantsVery low
Intervention not reported
Incidence persistent diarrhoea · patients with diarrhoea in children with HIV infection
1 finding from 1 review
- Prevention of diarrhoea in children with HIV infection or exposure to maternal HIV infection 2010 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 209 participantsLow
Intervention not reported
Severity diarrhoea by history and or physical exam · patients with diarrhoea in children with HIV infection
1 finding from 1 review
- Prevention of diarrhoea in children with HIV infection or exposure to maternal HIV infection 2010 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 239 participantsVery low
Intervention not reported
Respiratory infections history and/or physical exam · patients with diarrhoea in children with HIV infection
1 finding from 1 review
- Prevention of diarrhoea in children with HIV infection or exposure to maternal HIV infection 2010 · Cochrane Headline outcomes onlyno estimate extracted3 studies · 267 participantsLow