Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,615 questions · 1,673 findings · 190 reviews · Headline outcomes only

No studies found 278 · 16.6%GRADE not reported 85 · 5.1%Very low 328 · 19.6%Low 460 · 27.5%Moderate 402 · 24%High 120 · 7.2%

Inferior oblique disinsertion vs anterior transposition

Proportion of participants with anomalous head position preoperatively with residual head tilt postoperatively · people with unilateral superior oblique palsy

It is very uncertain whether inferior oblique disinsertion changes proportion of participants with anomalous head position… compared with anterior transposition (very low certainty).

1 finding from 1 review

Sugammadex (any dose) vs neostigmine (any dose)

Overall signs of postoperative residual paralysis · Adult patients, ASA I‐IV, who received non‐depolarizing NMBAs

Sugammadex (any dose) probably leads to lower overall signs of postoperative residual paralysis compared with neostigmine (any dose) (moderate certainty).

1 finding from 1 review

Sugammadex 2.0 mg/kg vs neostigmine (any dose)

Risk of adverse events and serious adverse eventsb, bradycardia, PONV, and signs of residual neuromuscular blockade · Adult patients, ASA I‐IV, who received non‐depolarizing NMBAs

The review found no eligible studies for this question.

1 finding from 1 review

Sugammadex 4.0 mg/kg vs neostigmine (any dose)

Risk of adverse events and serious adverse eventsb, bradycardia, PONV, and signs of residual neuromuscular blockade · Adult patients, ASA I‐IV, who received non‐depolarizing NMBAs

The review found no eligible studies for this question.

1 finding from 1 review