Streptococcus mutans load in the oral cavity (saliva and/or dental plaque) · Adults and children (general population)
Xylitol-only sugar-free gum significantly reduced Streptococcus mutans load versus pooled controls (SMD -0.46, 95% CI -0.64 to -0.28; 12 trials, I2 43%); certainty not formally graded.
1 finding from 1 review
Intervention not reported
Dental caries prevalence · General population (children and adults) in East Africa
Caries prevalence was lowest in Tanzania at 30.7% (95% CI 21.5 to 39.9); certainty not graded.
1 finding from 1 review
Initiation of white spot lesions (WSL), visual-tactile assessment · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances
For resin-based bonding agents, fluoride release did not significantly change WSL initiation (RR 0.97); subgroup not separately GRADE-rated.
1 finding from 1 review
Retention success rate · Children with primary molars requiring proximal (Class II) restorations
For the Rubber dam isolation: Yes subgroup, the 24-month retention success rate was 0.931 (95% CI 0.834-0.973; ungraded).
21 findings from 1 review
Proportion 0.931 [0.834, 0.973]
10 studies
GRADE not reported
Proportion 0.867 [0.779, 0.924]
24 studies
GRADE not reported
Proportion 0.805 [0.674, 0.892]
16 studies
GRADE not reported
Show 18 more findings
Proportion 0.934 [0.859, 0.971]
11 studies
GRADE not reported
Proportion 0.824 [0.672, 0.914]
8 studies
GRADE not reported
Proportion 0.554 [0.168, 0.885]
2 studies
GRADE not reported
Proportion 0.649 [0.488, 0.783]
8 studies
GRADE not reported
Proportion 0.950 [0.639, 0.995]
1 study
GRADE not reported
Proportion 0.879 [0.803, 0.928]
27 studies
GRADE not reported
Proportion 0.935 [0.726, 0.987]
3 studies
GRADE not reported
Proportion 0.904 [0.474, 0.989]
3 studies
GRADE not reported
Proportion 0.949 [0.868, 0.981]
7 studies
GRADE not reported
Proportion 0.826 [0.605, 0.937]
10 studies
GRADE not reported
Proportion 0.839 [0.764, 0.893]
34 (27 observed + 7 imputed) studies
GRADE not reported
Proportion 0.936 [0.895, 0.961]
19 studies
GRADE not reported
Proportion 0.854 [0.718, 0.931]
15 studies
GRADE not reported
Proportion 0.897 [0.792, 0.952]
12 studies
GRADE not reported
Proportion 0.956 [0.865, 0.986]
5 studies
GRADE not reported
Proportion 0.973 [0.695, 0.998]
2 studies
GRADE not reported
Proportion 0.851 [0.716, 0.929]
15 studies
GRADE not reported
Proportion 0.895 [0.828, 0.938]
25 studies
GRADE not reported
Dental caries susceptibility · Ethnicity: Caucasian (n=2) individuals with caries/high caries and controls
The pooled odds ratio was 1.63 (95% CI 0.67 to 4.01).
1 finding from 1 review
OR 1.63 [0.67, 4.01]
2 studies
GRADE not reported
Intervention not reported
Incidence of microleakage: Er,Cr:YSGG vs traditional bur (whole marginal line)
1 finding from 1 review
Qualitative NR [NR, NR]
1 study
GRADE not reported
Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
No significant association between AG genotype vs AA genotype of ENAM rs1264848 and dental caries susceptibility (AG vs AA model: OR 1.21, 95% CI 0.88-1.65); certainty not graded.
2 findings from 1 review
Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
No significant association between TT genotype vs CC genotype of AMELX rs6639060 and dental caries susceptibility (TT vs CC model: OR 1.04, 95% CI 0.43-2.51) in the Age group: Adults subgroup; certainty not graded.
3 findings from 1 review
Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
No significant association between CT genotype vs CC genotype of AMELX rs946252 and dental caries susceptibility (CT vs CC model: OR 2.80, 95% CI 0.93-8.43) in the Ethnicity: Caucasian subgroup; certainty not graded.
4 findings from 1 review
Show 1 more finding
Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
No significant association between GG genotype vs AA + AG genotype of LTF rs1126478 and dental caries susceptibility (GG vs AA + AG model: OR 0.95, 95% CI 0.80-1.13) in the Age group: Children subgroup; certainty not graded.
4 findings from 1 review
Show 1 more finding
OR 0.92 [0.77, 1.10]
2 studies
GRADE not reported
Dental caries susceptibility · Age group: Children (n=4) individuals with caries/high caries and controls
The pooled odds ratio was 0.98 (95% CI 0.87 to 1.10).
1 finding from 1 review
OR 0.98 [0.87, 1.10]
4 studies
GRADE not reported
Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
The CT genotype of AMELX rs17878486 was associated with increased dental caries risk (CT vs CC model: OR 5.11, 95% CI 1.33-19.72) in the Ethnicity: Mixed subgroup; certainty not graded.
6 findings from 1 review
Show 3 more findings
Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
No significant association between GG genotype vs AA + AG genotype of ENAM rs3796704 and dental caries susceptibility (GG vs AA + AG model: OR 1.05, 95% CI 0.66-1.68) in the Control group: Low caries subgroup; certainty not graded.
4 findings from 1 review
Show 1 more finding
Intervention not reported
Absence of recurrent caries success rate
1 finding from 1 review
Dental caries susceptibility · Ethnicity: Caucasian (n=2) individuals with caries/high caries and controls
The pooled odds ratio was 0.95 (95% CI 0.35 to 2.55).
1 finding from 1 review
OR 0.95 [0.35, 2.55]
2 studies
GRADE not reported
Intervention not reported
Absence of recurrent caries success rate
1 finding from 1 review
Intervention not reported
Absence of recurrent caries success rate
1 finding from 1 review
Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
No significant association between CT + TT genotype (T-allele carriers) vs CC genotype of AMELX rs946252 and dental caries susceptibility (CT + TT vs CC model: OR 1.63, 95% CI 0.67-4.01) in the Ethnicity: Caucasian subgroup; certainty not graded.
4 findings from 1 review
Show 1 more finding
Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
No significant association between T allele vs C allele of AMELX rs946252 and dental caries susceptibility (T vs C model: OR 0.99, 95% CI 0.53-1.86) in the Ethnicity: Mixed subgroup; certainty not graded.
5 findings from 1 review
Show 2 more findings
Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
No significant association between G allele vs A allele of ENAM rs3796704 and dental caries susceptibility (G vs A model: OR 1.11, 95% CI 0.57-2.15) in the Ethnicity: Mixed subgroup; certainty not graded.
4 findings from 1 review
Show 1 more finding