Number of participants with any adverse events№ of participants: 102(2 RCTs) · idiopathic hypersomnia
Modafinil showed no clear difference in number of participants with any adverse events№ of participants:… compared with placebo (low certainty).
1 finding from 1 review
OR 1.68 [0.28, 9.94]
Studies not reported
Low
Daytime sleepiness (ESS): change from baseline. · idiopathic hypersomnia
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Sleepiness · idiopathic hypersomnia
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Frequency of incontinence episodes · children aged 6 to 12 years with overactive bladder with urge incontinence
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Objective measurement of volume of incontinent episodes · children aged 6 to 12 years with overactive bladder with urge incontinence
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Resource implications (e.g. cost of incontinence management methods) · children aged 6 to 12 years with overactive bladder with urge incontinence
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Quality of life measurements · children aged 6 to 12 years with overactive bladder with urge incontinence
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse effects · children aged 6 to 12 years with overactive bladder with urge incontinence
1 finding from 1 review
Intervention not reported
Clearance of proven sepsis · neonates with suspected or proven sepsis
It is very uncertain whether the intervention changes clearance of proven sepsis (very low certainty).
1 finding from 1 review
Intervention not reported
Failure to achieve peak levels of at least 5 microgram/ml (measured 0.5 to one hour after administration of any dose of gentamicin) · neonates with suspected or proven sepsis
The intervention probably leads to lower failure to achieve peak levels of at least 5 microgram/ml (measured… (moderate certainty).
1 finding from 1 review
Intervention not reported
Nephrotoxicity (End of study period or before discharge) · neonates with suspected or proven sepsis
1 finding from 1 review
Intervention not reported
Ototoxicity (End of study period or before discharge) · neonates with suspected or proven sepsis
It is very uncertain whether the intervention changes ototoxicity (End of study period or before discharge) (very low certainty).
1 finding from 1 review
Intervention not reported
Failure to achieve trough levels of ≤2 microgram/ml ( · neonates with suspected or proven sepsis
The intervention probably leads to lower failure to achieve trough levels of ≤2 microgram/ml ( (moderate certainty).
1 finding from 1 review
Intervention not reported
Primary: Child intellectual development (cognitive ability) As assessed by 4 modified subscales of the British Ability Scale, which were summed for this review · children younger than five years of age
1 finding from 1 review
Intervention not reported
Primary: Child Intellectual development (attainment of educational goals) · children younger than five years of age
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Secondary: Child behaviour · children younger than five years of age
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Secondary: Disrupted child attachment · children younger than five years of age
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Secondary: Paid parental employment · children younger than five years of age
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Child cognitive ability As assessed by the Griffith Mental Development scale at 18‐month · children younger than five years of age and their families
It is very uncertain whether the intervention changes child cognitive ability As assessed by the Griffith Mental… (very low certainty).
1 finding from 1 review
Intervention not reported
Child psychosocial development Parents reporting their child develops abnormally · children younger than five years of age and their families
It is very uncertain whether the intervention changes child psychosocial development Parents reporting their child… (very low certainty).
1 finding from 1 review