Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

4,411 questions · 5,986 findings · 226 reviews · Oral Health

No studies found 1,305 · 21.8%GRADE not reported 2,988 · 49.9%Very low 1,030 · 17.2%Low 476 · 8%Moderate 156 · 2.6%High 31 · 0.5%

Ranked among the 5,000 newest matching findings; add words or filters to narrow the search.

Intraligamental injection local anaesthetic vs no treatment

Intraoperative or postoperative bleeding · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Powered toothbrush (any mode of action) vs Manual toothbrush

Gingivitis · Individuals of any age with no reported disability that might affect toothbrushing (including people wearing orthodontic appliances)

Powered toothbrush (any mode of action) probably leads to lower gingivitis score (1 to 3 months) compared with manual toothbrush (moderate certainty).

2 findings from 1 review

Dual mini-screw implant vs Single mini-screw implant

Duration of space closure · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage

Dual mini-screw implant showed no clear difference in duration of space closure compared with single mini-screw implant; GRADE not reported.

1 finding from 1 review

NobelActive internal connection implants vs NobelReplace implants

Marginal bone level change · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year

NobelActive internal connection implants showed no clear difference in marginal bone level change compared with nobelReplace implants; GRADE not reported.

1 finding from 1 review

Low‐level laser therapy vs Placebo (sham) laser therapy

Mechanosensory perception (load in grams to elicit sensation; Semmes Weinstein monofilaments) · Patients of any age in any setting requiring intervention for iatrogenic injury to the inferior alveolar or lingual nerve

Low-level laser therapy (photon-plus GaAlAs diode laser; 70 mW… led to higher mechanosensory perception (load in grams to elicit sensation; Semmes… compared with placebo (sham) laser therapy; GRADE not reported.

1 finding from 1 review

Infiltration injection LA and intraligamental injection LA (3-arm) vs no treatment

Parental satisfaction · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Psychological / counselling interventions (counselling, acupuncture, cognitive behavioural therapy, relaxation therapy, behaviour modification, electromyographic biofeedback, hypnosis, re-education) vs Another intervention, or no intervention

Outcome not reported · Patients of any age in any setting requiring intervention for iatrogenic injury to the inferior alveolar or lingual nerve

The review found no eligible studies for this question.

1 finding from 1 review

Infiltration injection local anaesthetic vs no treatment or placebo

Participant satisfaction · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Hand mallet (osteotomes) vs Electric mallet

Implant failure · Patients undergoing one-stage crestal maxillary sinus lift without bone grafts (baseline residual bone height about 6.5 mm)

Hand mallet (osteotomes) showed no clear difference in implant failure compared with electric mallet; GRADE not reported.

1 finding from 1 review

Primary outcome: topical local anaesthetics vs placebo or no treatment

Intraoperative or postoperative bleeding · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…
1 finding from 1 review

Rebamipide (systemic; 300 mg daily) vs placebo

Global aphthae count and pain score · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care
1 finding from 1 review
  • Matsuda 2003 (rebamipide 300 mg daily vs placebo, 35 patients; high risk of reporting bias; concomitant treatments): authors stated that rebamipide improved the global evaluation aphthae count and global evaluation…
    1 study · 35 participants
    GRADE not reported

Etanercept vs Placebo (subcutaneous)

Mean number of oral ulcers · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care
1 finding from 1 review
  • Interventions for managing oral ulcers in Behçet's disease 2014 · Cochrane All outcomes
    Males only
    Melikoglu 2005 (etanercept 25 mg s.c. twice weekly for 4 weeks vs placebo, 40 male patients; high risk of reporting bias): authors reported a statistically significant difference in mean number of oral ulcers with…
    1 study · 40 participants
    GRADE not reported

Topical interventions (sucralfate, interferon-alpha, cyclosporin A) vs placebo

Episode frequency associated with oral ulcers · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care
1 finding from 1 review
  • SoF (topical interventions vs placebo), grouped comment spanning all four listed outcomes (verbatim): "5 placebo-controlled trials evaluated topical interventions (sucralfate suspension (2 trials), interferon-alpha (2…
    Studies not reported
    GRADE not reported

Frankel's function regulator-4 (FR-4) with lip-seal training vs no treatment

Signs and symptoms of respiratory disease · Children and adolescents (over 80% aged 16 years or younger at treatment start) with anterior open bite (lack of vertical overlap or…

The review found no eligible studies for this question.

1 finding from 1 review

One-stage crestal-approach sinus lift with autogenous bone and 8 mm implants vs Lateral-window sinus lift with 50% autogenous bone/50% Bio-Oss and implants at least 10 mm long

Prosthesis failure · Patients with 3 to 6 mm of residual bone height at the sinus floor

One-stage crestal-approach sinus lift with autogenous bone and 8 mm… showed no clear difference in prosthesis failure compared with lateral-window sinus lift with 50% autogenous bone/50% Bio-Oss and…; GRADE not reported.

1 finding from 1 review

Infiltration injection local anaesthetic vs no treatment or placebo

Intraoperative or postoperative bleeding · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…
1 finding from 1 review

Topical interventions (sucralfate, interferon-alpha, cyclosporin A) vs placebo

Safety of the intervention (adverse effects) · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care
1 finding from 1 review
  • SoF (topical interventions vs placebo), grouped comment spanning all four listed outcomes (verbatim): "5 placebo-controlled trials evaluated topical interventions (sucralfate suspension (2 trials), interferon-alpha (2…
    Studies not reported
    GRADE not reported

Repair of a defective amalgam restoration in a permanent molar or premolar tooth (with amalgam) vs Replacement of a defective amalgam restoration in a permanent molar or premolar tooth (with amalgam)

Perioperative or postoperative pain or discomfort · Adults (16 years or over) with one or more defective amalgam restoration(s) in a molar or premolar tooth/teeth

The review found no eligible studies for this question.

1 finding from 1 review

Sinus lift with bone graft (granular Bio-Oss) vs Sinus lift without bone graft (Inion resorbable rigid barrier maintaining space / no bone)

Prosthesis failure · Patients with an atrophic maxillary sinus requiring augmentation (1 to 5 mm residual bone height)

Sinus lift with bone graft (granular Bio-Oss) showed no clear difference in prosthesis failure compared with sinus lift without bone graft (Inion resorbable rigid barrier…; GRADE not reported.

1 finding from 1 review