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Evidence found and GRADE certainty

4,411 questions · 5,986 findings · 226 reviews · Oral Health

No studies found 1,305 · 21.8%GRADE not reported 2,988 · 49.9%Very low 1,030 · 17.2%Low 476 · 8%Moderate 156 · 2.6%High 31 · 0.5%

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Sucralfate suspension (topical) vs Placebo suspension

Time to complete healing · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care

Sucralfate suspension (topical) showed no clear difference in healing time compared with placebo suspension; GRADE not reported.

1 finding from 1 review

Primary outcome: topical local anaesthetics vs placebo or no treatment

Postoperative pain or distress · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…
1 finding from 1 review

Powered toothbrush, counter oscillation action vs Manual toothbrush

Plaque · Individuals of any age with no reported disability that might affect toothbrushing (including people wearing orthodontic appliances)

Powered toothbrush, counter oscillation action led to lower plaque score (>3 months) compared with manual toothbrush; GRADE not reported.

2 findings from 1 review

Repair of a defective amalgam restoration in a permanent molar or premolar tooth (with amalgam) vs Replacement of a defective amalgam restoration in a permanent molar or premolar tooth (with amalgam)

Patient satisfaction (measured by patient satisfaction or aesthetic scales) · Adults (16 years or over) with one or more defective amalgam restoration(s) in a molar or premolar tooth/teeth

The review found no eligible studies for this question.

1 finding from 1 review

Sucralfate suspension (topical) vs Placebo suspension

Number of episodes · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care

Sucralfate suspension (topical) showed no clear difference in number of episodes compared with placebo suspension; GRADE not reported.

1 finding from 1 review

Maxillary sinus lift (augmentation) with long implants vs Short implants (5 to 8.5 mm) without sinus augmentation

Augmentation procedure failure · Patients with missing teeth and an atrophic posterior maxilla, with residual bone height between 4 and 9 mm below the maxillary sinus
1 finding from 1 review

Sucralfate suspension (topical) vs Placebo suspension

Pain (0-3 scale) · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care

Sucralfate suspension (topical) showed no clear difference in pain (0-3 scale) compared with placebo suspension; GRADE not reported.

1 finding from 1 review

Frankel's function regulator-4 (FR-4) with lip-seal training vs no treatment

Patient satisfaction · Children and adolescents (over 80% aged 16 years or younger at treatment start) with anterior open bite (lack of vertical overlap or…

The review found no eligible studies for this question.

1 finding from 1 review

Astra TiO2-blasted titanium screws vs Branemark turned titanium screws

Marginal bone level change · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year

Astra TiO2-blasted titanium screws showed no clear difference in marginal bone level change compared with branemark turned titanium screws; GRADE not reported.

1 finding from 1 review

MegaGen EZ Plus blasted standard implants vs MegaGen EZ Plus calcium-incorporated (Xpeed) implants

Marginal bone level change · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year

MegaGen EZ Plus blasted standard implants showed no clear difference in marginal bone level change compared with megaGen EZ Plus calcium-incorporated (Xpeed) implants; GRADE not reported.

1 finding from 1 review

Maxillary sinus lift (augmentation) with long implants vs Short implants (5 to 8.5 mm) without sinus augmentation

Implant failure · Patients with missing teeth and an atrophic posterior maxilla, with residual bone height between 4 and 9 mm below the maxillary sinus

Maxillary sinus lift (augmentation) with long implants showed no clear difference in implant failure compared with short implants (5 to 8.5 mm) without sinus augmentation (moderate certainty).

1 finding from 1 review

Aciclovir (systemic; 800 mg 5x/day for 1 week then 400 mg 2x/day for 11 weeks) vs placebo

Episode frequency associated with oral ulcers · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care
1 finding from 1 review
  • Davies 1988 (aciclovir vs placebo, 36 patients, cross-over; high risk of reporting bias; concomitant treatments): data were not presented in a usable format; authors reported no statistically significant difference in…
    1 study · 36 participants
    GRADE not reported

Interferon-alpha (topical lozenges) vs placebo

Total number of oral ulcers · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care

Interferon-alpha (topical; hydrogel or lozenges) showed no clear difference in total number of oral ulcers compared with placebo; GRADE not reported.

1 finding from 1 review

One-stage crestal-approach sinus lift with autogenous bone and 8 mm implants vs Lateral-window sinus lift with 50% autogenous bone/50% Bio-Oss and implants at least 10 mm long

Partial graft loss · Patients with 3 to 6 mm of residual bone height at the sinus floor

One-stage crestal-approach sinus lift with autogenous bone and 8 mm… showed no clear difference in partial graft loss compared with lateral-window sinus lift with 50% autogenous bone/50% Bio-Oss and…; GRADE not reported.

1 finding from 1 review

Infiltration injection local anaesthetic vs no treatment or placebo

Lip or cheek biting · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…
1 finding from 1 review

Primary outcome: topical local anaesthetics vs placebo or no treatment

Physiological parameters (cardiac/respiratory events; type and volume of GA drug) · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Dual mini-screw implant vs Single mini-screw implant

Success of the anchorage device · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage

Dual mini-screw implant showed no clear difference in success of the anchorage device compared with single mini-screw implant; GRADE not reported.

1 finding from 1 review

Repair of a defective resin composite restoration in a permanent molar or premolar tooth (with resin composite) vs Replacement of a defective resin composite restoration in a permanent molar or premolar tooth (with resin composite)

Success or failure of restoration (as defined by the USPHS criteria) · Adults (16 years or over) with one or more defective resin composite restoration(s) in a molar or premolar tooth/teeth

The review found no eligible studies for this question.

1 finding from 1 review

One-stage lateral sinus lift with monocortical autogenous bone blocks (iliac crest) vs Two-stage lateral sinus lift with autogenous particulate bone (iliac crest)

Implant failure · Patients with 2 to 7 mm of residual alveolar bone height in the edentulous maxillary sinus floor

One-stage lateral sinus lift with monocortical autogenous bone… showed no clear difference in implant failure compared with two-stage lateral sinus lift with autogenous particulate bone (iliac…; GRADE not reported.

1 finding from 1 review