Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,749 questions · 14,273 findings · 834 reviews

No studies found 3,655 · 25.6%GRADE not reported 2,115 · 14.8%Very low 3,646 · 25.5%Low 3,034 · 21.3%Moderate 1,503 · 10.5%High 320 · 2.2%

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Arginine butyrate plus standard care alone vs usual care

Ulcer healing · individuals with sickle cell disease and a leg ulcer

It is very uncertain whether arginine butyrate plus standard care alone changes complete leg ulcer closure (defined as 100% epithelization or skin… compared with standard care alone (very low certainty).

1 finding from 1 review

Primary‐level worker‐led collaborative care vs usual care

CMD symptoms ‐ intermediate term (1 to 6 months post intervention) Measured by change in CIS‐Rg; GHQ‐12i; HDRSc; PHQ‐9e,j,k scores from baseline (greater decline = greater improvement) · adults with common mental disorders
1 finding from 1 review