Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

461 questions · 473 findings · 36 reviews · HIV/AIDS

No studies found 38 · 8%GRADE not reported 9 · 1.9%Very low 126 · 26.6%Low 127 · 26.8%Moderate 152 · 32.1%High 21 · 4.4%

Intervention not reported

HIV infection (all studies together, regardless of sexual role) Lab test or self report · Men who have sex with men and transgender persons

The intervention showed no clear difference in HIV infection (all studies together, regardless of sexual role) Lab… (low certainty).

1 finding from 1 review

Intervention not reported

HIV infection (mainly receptive anal sex) · Men who have sex with men and transgender persons

It is very uncertain whether the intervention changes HIV infection (mainly receptive anal sex) (very low certainty).

1 finding from 1 review

Intervention not reported

HIV infection (mainly insertive anal sex) · Men who have sex with men and transgender persons

The intervention may leads to lower HIV infection (mainly insertive anal sex) (low certainty).

1 finding from 1 review

Intervention not reported

Herpes simplex virus ‐ 1 · Men who have sex with men and transgender persons

It is very uncertain whether the intervention changes herpes simplex virus ‐ 1 (very low certainty).

1 finding from 1 review

Intervention not reported

Herpes simplex virus ‐ 2 · Men who have sex with men and transgender persons

It is very uncertain whether the intervention changes herpes simplex virus ‐ 2 (very low certainty).

1 finding from 1 review

Intervention not reported

Consistent condom use ‐ 3 months Self‐report · patients with women living with HIV

The intervention showed no clear difference in consistent condom use ‐ 3 months Self‐report (low certainty).

1 finding from 1 review

Intervention not reported

Consistent condom use ‐ 6 months Self‐report · patients with women living with HIV

The intervention showed no clear difference in consistent condom use ‐ 6 months Self‐report (low certainty).

1 finding from 1 review

Intervention not reported

Consistent condom use ‐ 12 months Self‐report · patients with women living with HIV

The intervention showed no clear difference in consistent condom use ‐ 12 months Self‐report (low certainty).

1 finding from 1 review

Lactobacillus vs placebo

Episodes of confirmed vaginal candidiasis fungal smear · prevention and treatment of vulvovaginal candidiasis in women with HIV infection

Lactobacillus showed no clear difference in episodes of confirmed vaginal candidiasis fungal smear compared with placebo (low certainty).

1 finding from 1 review

Clotrimazole (partially absorbed from GI tract) vs placebo

Episodes of confirmed vaginal candidiasis fungal smear · prevention and treatment of vulvovaginal candidiasis in women with HIV infection

Clotrimazole showed no clear difference in episode of confirmed vaginal candidiasis fungal smear compared with placebo (low certainty).

1 finding from 1 review

Azoles vs placebo

Episodes of confirmed vaginal candidiasis fungal smear · prevention and treatment of vulvovaginal candidiasis in women with HIV infection

It is very uncertain whether azoles changes episode of confirmed vaginal candidiasis Fungal Smears compared with placebo (very low certainty).

1 finding from 1 review

Intervention not reported

Episode of confirmed vaginal candidiasis ‐ Upto 12 months Fungal smears · prevention and treatment of vulvovaginal candidiasis in women with HIV infection

The intervention probably leads to lower episode of confirmed vaginal candidiasis ‐ Upto 12 months Fungal… (moderate certainty).

1 finding from 1 review

Intervention not reported

Episode of confirmed vaginal candidiasis ‐ Upto 24 Months Fungal smears · prevention and treatment of vulvovaginal candidiasis in women with HIV infection

The intervention probably leads to lower episode of confirmed vaginal candidiasis ‐ Upto 24 Months Fungal… (moderate certainty).

1 finding from 1 review

Intervention not reported

Emergence of non albicans species of Candida ‐ At 12 months Fungal Smears · prevention and treatment of vulvovaginal candidiasis in women with HIV infection

The intervention showed no clear difference in emergence of non albicans species of Candida ‐ At 12 months Fungal… (moderate certainty).

1 finding from 1 review