Cochrane · systematic review · CD007496

Male circumcision for prevention of homosexual acquisition of HIV in men

Wiysonge, CS, Kongnyuy, EJ, Shey, M, et al. · Cochrane Database of Systematic Reviews · 2011 · Cochrane Library

HIV/AIDSAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 3 · 50%Low 3 · 50%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Male circumcision for prevention of HIV and other STIs among men who have sex with men and transgender people

Population: Men who have sex with men and transgender persons
6 questions
OutcomeEffectEvidenceStatus / GRADE
HIV infection (all studies together, regardless of sexual role) Lab test or self report
OR 0.86 [0.7, 1.06]20 studies · 64915 participantsLow
Downgraded: publication bias
HIV infection (mainly receptive anal sex)
OR 1.2 [0.63, 2.29]3 studies · 876 participantsVery low
Downgraded: publication bias
HIV infection (mainly insertive anal sex)
OR 0.27 [0.17, 0.44]7 studies · 2098 participantsLow
Downgraded: publication bias
Syphilis
OR 0.96 [0.82, 1.13]6 studies · 31174 participantsLow
Downgraded: publication bias
Herpes simplex virus ‐ 1
OR 0.9 [0.53, 1.52]2 studies · 2740 participantsVery low
Downgraded: publication bias
Herpes simplex virus ‐ 2
OR 0.86 [0.62, 1.21]4 studies · 10285 participantsVery low
Downgraded: publication bias