Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,340 questions · 1,512 findings · 205 reviews

No studies found 317 · 21%GRADE not reported 358 · 23.7%Very low 356 · 23.5%Low 271 · 17.9%Moderate 173 · 11.4%High 37 · 2.4%

Intervention not reported

Letter with fixed appointment versus letter with open invitation to make appointment: uptake of screening · women for cervical screening

The intervention probably leads to higher letter with fixed appointment versus letter with open invitation to… (moderate certainty).

1 finding from 1 review

Capecitabine‐containing regimens vs chemotherapy regimens without capecitabine

Febrile neutropenia · neoadjuvant treatment of ER‐positive vs ER‐negative breast cancer

Capecitabine‐containing regimens showed no clear difference in febrile neutropenia compared with non‐capecitabine‐containing regimens (moderate certainty).

1 finding from 1 review

Capecitabine‐containing regimens vs non‐capecitabine‐containing regimens or no chemotherapy

Febrile neutropenia · patients with early breast cancer

Capecitabine‐containing regimens probably leads to lower febrile neutropenia compared with non‐capecitabine‐containing regimens or no chemotherapy (moderate certainty).

1 finding from 1 review

Systemic sclerosis (SSc / scleroderma) vs SSc-free individuals (controls)

Maximal mouth opening (interincisal distance) · Adults (general and hospital populations assessed in case-control studies)

Systemic sclerosis patients have significantly reduced mouth opening compared with controls (SMD -1.06); certainty ungraded.

1 finding from 1 review

Summary of findings: Fibrin sealant vs Conventional (simple interrupted) suturing

Trismus / maximum mouth opening (mean) · Adults with mandibular third molars requiring removal

Fibrin sealant led to higher trismus / maximum mouth opening (mean) compared with conventional suturing; GRADE not reported.

1 finding from 1 review

Drain use vs No drain

Maximal mouth opening (interincisal distance) · Adults with mandibular third molars requiring removal

Surgical drain (tube or gauze) led to higher maximum mouth opening (mean) compared with no drain; GRADE not reported.

1 finding from 1 review