Findings

What do systematic reviews say?

1,155 questions · 1,191 findings · 195 reviews · Headline outcomes only

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No studies found 209 · 17.5%GRADE not reported 51 · 4.3%Very low 256 · 21.5%Low 273 · 22.9%Moderate 284 · 23.8%High 118 · 9.9%

Cognitive training vs alternative treatment

Change in disease progression · people with mild to moderate dementia

1 finding from 1 review

Cognitive training for people with mild to moderate dementia 2019 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Cognitive training vs alternative treatment

Change in delayed memory · people with mild to moderate dementia

1 finding from 1 review

Cognitive training for people with mild to moderate dementia 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 73 participants
Very low

Cognitive training vs alternative treatment

Mood · people with mild to moderate dementia

1 finding from 1 review

Cognitive training for people with mild to moderate dementia 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 39 participants
Low

Cognitive training vs alternative treatment

Change in capacity for activities of daily living · people with mild to moderate dementia

1 finding from 1 review

Cognitive training for people with mild to moderate dementia 2019 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Cognitive training vs alternative treatment

Change in mood and well‐being (caregiver) · people with mild to moderate dementia

1 finding from 1 review

Cognitive training for people with mild to moderate dementia 2019 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Cognitive training vs control immediately post intervention

Change in delayed memory · people with mild to moderate dementia

1 finding from 1 review

Cognitive training for people with mild to moderate dementia 2019 · Cochrane Headline outcomes only
no estimate extracted
11 studies · 543 participants
Very low

Cognitive training vs control immediately post intervention

Mood · people with mild to moderate dementia

1 finding from 1 review

Cognitive training for people with mild to moderate dementia 2019 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 577 participants
Very low

Cognitive training vs control immediately post intervention

Change in capacity for activities of daily living · people with mild to moderate dementia

1 finding from 1 review

Cognitive training for people with mild to moderate dementia 2019 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 687 participants
Low

Cognitive training vs control immediately post intervention

Participant burden (retention rates) · people with mild to moderate dementia

Cognitive training showed no clear difference in participant burden (retention rates) compared with control immediately post intervention (low certainty).

1 finding from 1 review

Cognitive training for people with mild to moderate dementia 2019 · Cochrane Headline outcomes only
OR 0.73 [0.37, 1.43]
17 studies · 1282 participants
Low

Cognitive training vs control immediately post intervention

Change in mood and well‐being (caregiver) · people with mild to moderate dementia

1 finding from 1 review

Cognitive training for people with mild to moderate dementia 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 36 participants
Moderate

Cognitive training vs control

Change in a global measure of cognition (composite) · people with mild to moderate dementia

1 finding from 1 review

Cognitive training for people with mild to moderate dementia 2019 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 387 participants
Very low

Cognitive training vs control

Cognitive function · people with mild to moderate dementia

1 finding from 1 review

Cognitive training for people with mild to moderate dementia 2019 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 387 participants
Very low

Any antihypertensive drug vs no antihypertensive drugs/placebo

Maternal · women with mild to moderate hypertension during pregnancy

The review found no eligible studies for this question.

2 findings from 1 review

Antihypertensive drug therapy for mild to moderate hypertension during pregnancy 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found
Antihypertensive drug therapy for mild to moderate hypertension during pregnancy 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Any antihypertensive drug vs no antihypertensive drugs/placebo

Severe pre‐eclampsia · women with mild to moderate hypertension during pregnancy

It is very uncertain whether any antihypertensive drug changes severe pre‐eclampsia compared with no antihypertensive drugs/placebo (very low certainty).

1 finding from 1 review

Antihypertensive drug therapy for mild to moderate hypertension during pregnancy 2018 · Cochrane Headline outcomes only
RR 0.56 [0.15, 2.02]
3 studies · 416 participants
Very low

Any antihypertensive drug vs no antihypertensive drugs/placebo

Eclampsia · women with mild to moderate hypertension during pregnancy

It is very uncertain whether any antihypertensive drug changes eclampsia compared with no antihypertensive drugs/placebo (very low certainty).

1 finding from 1 review

Antihypertensive drug therapy for mild to moderate hypertension during pregnancy 2018 · Cochrane Headline outcomes only
RR 0.52 [0.13, 2.06]
7 studies · 713 participants
Very low

Any antihypertensive drug vs no antihypertensive drugs/placebo

Changed/stopped drugs due to maternal side‐effects · women with mild to moderate hypertension during pregnancy

Any antihypertensive drug showed no clear difference in changed/stopped drugs due to maternal side‐effects compared with no antihypertensive drugs/placebo (low certainty).

1 finding from 1 review

Antihypertensive drug therapy for mild to moderate hypertension during pregnancy 2018 · Cochrane Headline outcomes only
RR 1.93 [0.92, 4.06]
16 studies · 1503 participants
Low

Any antihypertensive drug vs no antihypertensive drugs/placebo

Elective delivery (induction of labour + elective caesarean section) · women with mild to moderate hypertension during pregnancy

Any antihypertensive drug showed no clear difference in elective delivery (induction of labour + elective caesarean section) compared with no antihypertensive drugs/placebo (moderate certainty).

1 finding from 1 review

Antihypertensive drug therapy for mild to moderate hypertension during pregnancy 2018 · Cochrane Headline outcomes only
RR 0.93 [0.84, 1.04]
4 studies · 710 participants
Moderate

Any antihypertensive drug vs no antihypertensive drugs/placebo

Fetal/neonatal/infant · women with mild to moderate hypertension during pregnancy

The review found no eligible studies for this question.

2 findings from 1 review

Antihypertensive drug therapy for mild to moderate hypertension during pregnancy 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found
Antihypertensive drug therapy for mild to moderate hypertension during pregnancy 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Any antihypertensive drug vs no antihypertensive drugs/placebo

Admission to neonatal or intensive care nursery · women with mild to moderate hypertension during pregnancy

Any antihypertensive drug showed no clear difference in admission to neonatal or intensive care nursery compared with no antihypertensive drugs/placebo (low certainty).

1 finding from 1 review

Antihypertensive drug therapy for mild to moderate hypertension during pregnancy 2018 · Cochrane Headline outcomes only
RR 1.01 [0.83, 1.22]
10 studies · 1570 participants
Low

Any antihypertensive drug vs no antihypertensive drugs/placebo

Severe hypertension · women with mild to moderate hypertension during pregnancy

Any antihypertensive drug probably leads to lower severe hypertension compared with no antihypertensive drugs/placebo (moderate certainty).

1 finding from 1 review

Antihypertensive drug therapy for mild to moderate hypertension during pregnancy 2018 · Cochrane Headline outcomes only
RR 0.49 [0.4, 0.6]
20 studies · 2558 participants
Moderate