Proportion of participants with adverse effects serious or severe enough to have caused withdrawal ‐ not reported · chronic palmoplantar pustulosis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Pruritus · chronic pruritus of unknown origin
Serlopitant 5 mg may leads to higher patient‐reported pruritus intensity compared with placebo (low certainty).
1 finding from 1 review
Sleep disturbances: number of participants with insomnia · chronic pruritus of unknown origin
It is very uncertain whether serlopitant 1 mg changes sleep disturbances: number of participants with insomnia compared with placebo (very low certainty).
1 finding from 1 review
Depression · chronic pruritus of unknown origin
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Patient satisfaction · chronic pruritus of unknown origin
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Pruritus · chronic pruritus of unknown origin
Serlopitant 0.25 mg showed no clear difference in patient‐reported pruritus intensity compared with placebo (low certainty).
1 finding from 1 review
Adverse events · chronic pruritus of unknown origin
It is very uncertain whether serlopitant 0.25 mg changes adverse events compared with placebo (very low certainty).
1 finding from 1 review
Health‐related quality of life · chronic pruritus of unknown origin
1 finding from 1 review
Sleep disturbances: number of participants with insomnia · chronic pruritus of unknown origin
It is very uncertain whether serlopitant 0.25 mg changes sleep disturbances: number of participants with insomnia compared with placebo (very low certainty).
1 finding from 1 review
Depression · chronic pruritus of unknown origin
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Patient satisfaction · chronic pruritus of unknown origin
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · chronic pruritus of unknown origin
It is very uncertain whether serlopitant 5 mg changes adverse events compared with placebo (very low certainty).
1 finding from 1 review
Health‐related quality of life · chronic pruritus of unknown origin
1 finding from 1 review
Sleep disturbances: number of participants with insomnia · chronic pruritus of unknown origin
It is very uncertain whether serlopitant 5 mg changes sleep disturbances: number of participants with insomnia compared with placebo (very low certainty).
1 finding from 1 review
Depression · chronic pruritus of unknown origin
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Patient satisfaction · chronic pruritus of unknown origin
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Pruritus · chronic pruritus of unknown origin
Serlopitant 1 mg showed no clear difference in patient‐reported pruritus intensity compared with placebo (low certainty).
1 finding from 1 review
Adverse events · chronic pruritus of unknown origin
It is very uncertain whether serlopitant 1 mg changes adverse events compared with placebo (very low certainty).
1 finding from 1 review
Health‐related quality of life · chronic pruritus of unknown origin
1 finding from 1 review
Primary: investigator‐rated good/excellent control of symptoms · participants with moderate to severe hand eczema
Corticosteroid creams/ointments: clobetasol propionate foam showed no clear difference in primary: investigator‐rated good/excellent control of symptoms compared with vehicle foam (moderate certainty).
1 finding from 1 review