Question · asked by 1 review
Serlopitant 5 mg vs placebo: Adverse events
- Population
- chronic pruritus of unknown origin
- Intervention
- Serlopitant 5 mg
- Comparison
- placebo
- Outcome
- Adverse events
It is very uncertain whether serlopitant 5 mg changes adverse events compared with placebo (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Serlopitant 5 mg vs placebo Adverse events · chronic pruritus of unknown origin It is very uncertain whether serlopitant 5 mg changes adverse events compared with placebo (very low certainty). Interventions for chronic pruritus of unknown origin (2020) · Cochrane Headline outcomes only | RR 1.48 [0.87, 2.5] | 1 study · 127 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for chronic pruritus of unknown origin 2020 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.