Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

644 questions · 665 findings · 65 reviews · Developmental, Psychosocial and Learning Problems

No studies found 168 · 25.3%GRADE not reported 23 · 3.5%Very low 251 · 37.7%Low 148 · 22.3%Moderate 70 · 10.5%High 5 · 0.8%

Home (point‐of‐use) fortification of foods with multiple micronutrient powders vs placebo or no intervention

Anaemia · preschool and school‐age children

Point‐of‐use fortification of foods with micronutrients powders (MNP) probably leads to lower anaemia (defined as haemoglobin < 110 g/L for children aged 24‐59… compared with no intervention or placebo (moderate certainty).

1 finding from 1 review

Home (point‐of‐use) fortification of foods with multiple micronutrient powders vs placebo or no intervention

Iron deficiency (using ferritin concentrations) · preschool and school‐age children

Point‐of‐use fortification of foods with micronutrients powders (MNP) probably leads to lower iron deficiency (defined by using ferritin concentrations less than… compared with no intervention or placebo (moderate certainty).

1 finding from 1 review

Home (point‐of‐use) fortification of foods with multiple micronutrient powders vs placebo or no intervention

Diarrhoea · preschool and school‐age children

Point‐of‐use fortification of foods with micronutrients powders (MNP) showed no clear difference in diarrhoea (≥ 3 liquid stools per day) compared with no intervention or placebo (low certainty).

1 finding from 1 review

Home (point‐of‐use) fortification of foods with multiple micronutrient powders vs placebo or no intervention

Any adverse effects (e.g. hypervitaminosis A, as defined by the trialists) · preschool and school‐age children

Point‐of‐use fortification of foods with micronutrients powders (MNP) showed no clear difference in adverse effects (any, as defined by trialists) compared with no intervention or placebo (moderate certainty).

1 finding from 1 review

Parent‐infant psychotherapy vs other (psychoeducational) parenting intervention: parent mental health and infant attachment

Infant attachment categories meta‐analysis: · participants with improving parental and infant mental health

It is very uncertain whether parent‐infant psychotherapy changes infant attachment categories meta‐analysis: compared with other (psychoeducational) parenting intervention: parent mental… (very low certainty).

2 findings from 1 review

Intermittent use of iron supplements vs placebo or no intervention

Anaemia · children under 12 years of age

Intermittent use of iron supplements probably leads to lower anaemia (haemoglobin below a cut‐off defined by trialists, taking… compared with placebo or no intervention (moderate certainty).

1 finding from 1 review

Intermittent use of iron supplements vs placebo or no intervention

Iron deficiency (using ferritin concentrations) · children under 12 years of age

It is very uncertain whether intermittent use of iron supplements changes iron deficiency (using ferritin concentrations) compared with placebo or no intervention (very low certainty).

1 finding from 1 review

Intermittent use of iron supplements vs placebo or no intervention

Iron status (ferritin concentrations in ng/mL) · children under 12 years of age

Intermittent use of iron supplements may leads to higher iron status (ferritin (μg/L) compared with placebo or no intervention (low certainty).

1 finding from 1 review

Summary of findings table ‐ Anger management vs waiting list control

Aggressive behaviour: severity of incidents: Aberrant Behaviour Checklist (ABC – irritability subscale – key worker report – post‐treatment (Analysis 1.2.1) · outwardly aggressive behaviour in people with intellectual disability
1 finding from 1 review

Summary of findings table ‐ Positive behavioural support vs treatment

Mental state: Common Mental Disorder (CMD) – at 6 months (Analysis 2.2.1) (CMD) · outwardly aggressive behaviour in people with intellectual disability

Summary of findings table ‐ Positive behavioural support showed no clear difference in mental state: Common Mental Disorder (CMD) – at 6 months (Analysis… compared with treatment (low certainty).

1 finding from 1 review