What do systematic reviews say?

Cuffed vs uncuffed tubes

• Cuffed versus uncuffed endotracheal tubes for general anaesthesia in children aged eight years and under 2017 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 70 participants
  Low

Cuffed vs uncuffed tubes

It is very uncertain whether cuffed changes need for corticosteroid to treat stridor (defined as the need to use… compared with uncuffed tubes (very low certainty).

• Cuffed versus uncuffed endotracheal tubes for general anaesthesia in children aged eight years and under 2017 · Cochrane Headline outcomes only
  RR 0.87 [0.51, 1.49]
  1 study · 102 participants
  Very low

Any intervention vs control

• Psychological preparation and postoperative outcomes for adults undergoing surgery under general anaesthesia 2016 · Cochrane Headline outcomes only
  no estimate extracted
  38 studies · 2713 participants
  Low

Any intervention vs control

• Psychological preparation and postoperative outcomes for adults undergoing surgery under general anaesthesia 2016 · Cochrane Headline outcomes only
  no estimate extracted
  14 studies · 1441 participants
  Very low

Any intervention vs control

• Psychological preparation and postoperative outcomes for adults undergoing surgery under general anaesthesia 2016 · Cochrane Headline outcomes only
  no estimate extracted
  36 studies · 3313 participants
  Low

Any intervention vs control

• Psychological preparation and postoperative outcomes for adults undergoing surgery under general anaesthesia 2016 · Cochrane Headline outcomes only
  no estimate extracted
  31 studies · 2496 participants
  Low

Entropy vs Standard care alone (surgery, antibiotics, oral rinse)

• Spectral entropy monitoring for adults and children undergoing general anaesthesia 2016 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 383 participants
  Moderate

Entropy vs Standard care alone (surgery, antibiotics, oral rinse)

• Spectral entropy monitoring for adults and children undergoing general anaesthesia 2016 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 3 participants
  GRADE not reported

Entropy vs Standard care alone (surgery, antibiotics, oral rinse)

• Spectral entropy monitoring for adults and children undergoing general anaesthesia 2016 · Cochrane Headline outcomes only
  no estimate extracted
  8 studies · 797 participants
  Moderate

Entropy vs Standard care alone (surgery, antibiotics, oral rinse)

• Spectral entropy monitoring for adults and children undergoing general anaesthesia 2016 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 166 participants
  Low

Entropy vs Standard care alone (surgery, antibiotics, oral rinse)

• Spectral entropy monitoring for adults and children undergoing general anaesthesia 2016 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 156 participants
  Moderate

Entropy vs Standard care alone (surgery, antibiotics, oral rinse)

• Spectral entropy monitoring for adults and children undergoing general anaesthesia 2016 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 170 participants
  Low

Intervention not reported

The intervention showed no clear difference in inhospital case fatality rate (moderate certainty).

• Nitrous oxide‐based techniques versus nitrous oxide‐free techniques for general anaesthesia 2015 · Cochrane Headline outcomes only
  OR 0.87 [0.61, 1.26]
  8 studies · 10148 participants
  Moderate

Intervention not reported

The intervention showed no clear difference in pneumonia (low certainty).

• Nitrous oxide‐based techniques versus nitrous oxide‐free techniques for general anaesthesia 2015 · Cochrane Headline outcomes only
  OR 1.68 [1, 2.81]
  8 studies · 2699 participants
  Low

Intervention not reported

The intervention leads to higher pulmonary atelectasis (high certainty).

• Nitrous oxide‐based techniques versus nitrous oxide‐free techniques for general anaesthesia 2015 · Cochrane Headline outcomes only
  OR 1.57 [1.18, 2.1]
  5 studies · 2400 participants
  High

Intervention not reported

The intervention showed no clear difference in myocardial infarction (high certainty).

• Nitrous oxide‐based techniques versus nitrous oxide‐free techniques for general anaesthesia 2015 · Cochrane Headline outcomes only
  OR 1.01 [0.84, 1.22]
  6 studies · 9246 participants
  High

Intervention not reported

The intervention showed no clear difference in stroke (moderate certainty).

• Nitrous oxide‐based techniques versus nitrous oxide‐free techniques for general anaesthesia 2015 · Cochrane Headline outcomes only
  OR 1.47 [0.86, 2.53]
  4 studies · 9142 participants
  Moderate

Intervention not reported

The intervention showed no clear difference in severe nausea and vomiting (low certainty).

• Nitrous oxide‐based techniques versus nitrous oxide‐free techniques for general anaesthesia 2015 · Cochrane Headline outcomes only
  OR 1.44 [0.97, 2.15]
  10 studies · 11045 participants
  Low

Intervention not reported

• Nitrous oxide‐based techniques versus nitrous oxide‐free techniques for general anaesthesia 2015 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 1103 participants
  Moderate

Intervention not reported

The intervention showed no clear difference in venous thromboembolism (moderate certainty).

• Nitrous oxide‐based techniques versus nitrous oxide‐free techniques for general anaesthesia 2015 · Cochrane Headline outcomes only
  OR 0.73 [0.45, 1.2]
  2 studies · 9004 participants
  Moderate