Dental caries prevalence · Children aged 12 years (plus or minus one year) in Africa
The pooled dental-caries prevalence was 0.3657 (95% CI 0.3065 to 0.4250); GRADE was not reported.
2 findings from 1 review
Prevalence 0.3657 [0.3065, 0.4250]
Studies not reported
GRADE not reported
Prevalence 0.356 [0.294, 0.417]
Studies not reported
GRADE not reported
Early childhood caries (ECC) - association with genetically predicted expression of SMIM10L1 (chr12p13.2) · Children up to age 5-6 years (European / European non-Hispanic ancestry); 843 ECC-affected vs 2124 unaffected across 5 cohorts (N=2974)
Genetically predicted expression of SMIM10L1 was significantly associated with ECC in the TWAS (p = 1.70e-7); genetic association, ungraded.
1 finding from 1 review
Enamel caries proportion · European adolescents aged 12 years
Pooled enamel caries proportion was 0.52 (I² = 100.0%).
1 finding from 1 review
Treatment failure (annual failure rate) · Children with previously unrestored, vital carious lesions in primary teeth (no pulp therapy); aged 1.5-11 years
Amalgam restorations in primary teeth showed a wide annual failure rate (1-28%) across 4 RCTs; the evidence is of low quality (high risk of bias; ungraded).
1 finding from 1 review
Dental caries prevalence · European adolescents aged 12–19 years
Caries prevalence at the dentine threshold was about 56% (pooled 0.56, 95% CI 0.43 to 0.68; 15 studies; not GRADE-rated).
7 findings from 1 review
Prevalence 0.56 [0.43, 0.68]
15 studies
GRADE not reported
Prevalence 0.49 [0.32, 0.67]
9 studies
GRADE not reported
Prevalence 0.57 [0.32, 0.81]
6 studies
GRADE not reported
Show 4 more findings
Development of >=1 new carious lesion (caries incidence) · Children with caries-free primary first molars (with or without caries on other teeth), aged 1-5 years (paediatric clinic/dental school,…
Glass ionomer-based sealant may leads to lower development of >=1 new carious lesion (caries incidence) compared with no sealant (low certainty).
2 findings from 1 review
Dental caries prevalence · European adolescents aged 12–19 years
Enamel-threshold caries prevalence in subgroup 'Region: non-Scandinavian' was 0.74 (95% CI 0.53 to 0.96; 11 studies).
11 findings from 1 review
Show 8 more findings
Prevalence 0.74 [0.57, 0.90]
17 studies
GRADE not reported
Prevalence 0.76 [0.65, 0.87]
11 studies
GRADE not reported
Prevalence 0.83 [0.75, 0.89]
7 studies
GRADE not reported
Prevalence 0.77 [0.65, 0.89]
22 studies · 84512 participants
GRADE not reported
Prevalence 0.74 [0.53, 0.96]
11 studies
GRADE not reported
Prevalence 0.72 [0.54, 0.89]
15 studies
GRADE not reported
Prevalence 0.90 [0.85, 0.94]
7 studies
GRADE not reported
Prevalence 0.78 [0.70, 0.87]
10 studies
GRADE not reported
Dental caries prevalence · European adolescents aged 12 years
Pooled caries prevalence was 0.69 (I² = 100.0%).
1 finding from 1 review
Oral hygiene measured by mean gingival scores · Primary school children (aged 3-16 years) attending primary school in low- and middle-income countries (LMICs)
The effect of school-based interventions on gingival scores is uncertain and not statistically significant (SMD 0.12; very low certainty).
1 finding from 1 review
Dental caries · Primary school children (aged 3-16 years) attending primary school in low- and middle-income countries (LMICs)
Among children aged 6-8 years, DMFT scores were significantly reduced (SMD -0.11); subgroup not separately GRADE-rated.
8 findings from 1 review
Effectiveness of primary school-based interventions in improving oral health of children in low- and middle-income… 2022 All outcomesPost-intervention; follow-up varied across studies (interventions ranged from <2 years to >=2 years and longer) · Primary schools in low- and middle-income countries (Southeast Asia, Africa, the Americas, Europe, eastern Mediterranean) · Age 6-8 years
SMD -0.11 [-0.17, -0.04]
Studies not reported
GRADE not reported
Effectiveness of primary school-based interventions in improving oral health of children in low- and middle-income… 2022 All outcomesPost-intervention; follow-up varied across studies (interventions ranged from <2 years to >=2 years and longer) · Primary schools in low- and middle-income countries (Southeast Asia, Africa, the Americas, Europe, eastern Mediterranean) · <=3 intervention activities
SMD -0.58 [-1.62, 0.45]
Studies not reported
GRADE not reported
Effectiveness of primary school-based interventions in improving oral health of children in low- and middle-income… 2022 All outcomes<2 years · Primary schools in low- and middle-income countries (Southeast Asia, Africa, the Americas, Europe, eastern Mediterranean) · Intervention duration <2 years
SMD 0.01 [-0.16, 0.18]
3 studies
GRADE not reported
Show 5 more findings
Annual increment in DMFS (D3) · Primary school children (aged 3-16 years) attending primary school in low- and middle-income countries (LMICs)
Oral-health-education interventions significantly reduced net increment in DMFS (SMD -1.05); no significant subgroup difference vs other interventions (P=0.74).
5 findings from 1 review
Effectiveness of primary school-based interventions in improving oral health of children in low- and middle-income… 2022 All outcomesPost-intervention; follow-up varied across studies (interventions ranged from <2 years to >=2 years and longer) · Primary schools in low- and middle-income countries (Southeast Asia, Africa, the Americas, Europe, eastern Mediterranean) · Intervention type: oral health education
SMD -1.05 [-2.03, -0.08]
3 studies
GRADE not reported
Effectiveness of primary school-based interventions in improving oral health of children in low- and middle-income… 2022 All outcomesPost-intervention; follow-up varied across studies (interventions ranged from <2 years to >=2 years and longer) · Primary schools in low- and middle-income countries (Southeast Asia, Africa, the Americas, Europe, eastern Mediterranean) · WHO health-promoting-schools framework
SMD -0.57 [-1.56, 0.42]
2 studies
GRADE not reported
Effectiveness of primary school-based interventions in improving oral health of children in low- and middle-income… 2022 All outcomesPost-intervention; follow-up varied across studies (interventions ranged from <2 years to >=2 years and longer) · Primary schools in low- and middle-income countries (Southeast Asia, Africa, the Americas, Europe, eastern Mediterranean) · Non-WHO-framework interventions
SMD -1.88 [-3.15, -0.60]
Studies not reported
GRADE not reported
Show 2 more findings
Caries distribution (individual/tooth/surface level) · European adolescents aged 12–19 years
Caries distribution was skewed at individual, tooth and surface levels and too heterogeneous to meta-analyze (narrative synthesis of 11 studies; not GRADE-rated).
1 finding from 1 review
No meta-analysis possible; caries distribution reported narratively from 11 studies as skewed at individual, tooth and surface levels, changing with age at tooth and surface level (Results – Caries distribution).
11 studies
GRADE not reported
Dental caries prevalence measured by dmft or DMFT/S score greater than one · Primary school children (aged 3-16 years) attending primary school in low- and middle-income countries (LMICs)
School-based interventions may reduce the prevalence of dental caries (RR 0.70, favouring intervention), but the certainty of evidence is very low.
3 findings from 1 review
Caries experience · European adolescents aged 13 years
Pooled caries experience was 1.45.
1 finding from 1 review
Dental caries prevalence · European adolescents aged 17 years
Pooled caries prevalence was 0.83 (I² = 87.2%).
1 finding from 1 review
Mean caries increment (mean number of new cavitated occlusal lesions) · Children with caries-free or non-cavitated carious lesion primary molars, aged 3-7 years (paediatric department, dental hospital, France)
1 finding from 1 review
Caries increment in permanent teeth · School children and adolescents (6-18 years) followed from primary dentition (baseline examination before 72 months of age)
Evidence on the association between sociodemographic/socioeconomic factors and permanent-teeth caries is weak and inconsistent (3 studies; could not be pooled; not GRADE-rated).
1 finding from 1 review
Treatment failure (annual failure rate) · Children with previously unrestored, vital carious lesions in primary teeth (no pulp therapy); aged 1.5-11 years
High-viscosity GIC had a wide annual failure rate (2.9-25.6%) and was outperformed by compomer/composite in some trials (3 RCTs); low quality of evidence (ungraded).
1 finding from 1 review
Caries experience (mean DMFT) · Children aged 12 years (plus or minus one year) in Africa
The pooled mean DMFT score was 1.0900 (95% CI 0.9143 to 1.2657); GRADE was not reported.
2 findings from 1 review
Mean DMFT 1.0900 [0.9143, 1.2657]
Studies not reported
GRADE not reported
Mean DMFT 1.1444 [0.9780, 1.3108]
Studies not reported
GRADE not reported
Early childhood caries (ECC) - association at lead SNP rs76823412 (8:134690570; nearest gene(s) ST3GAL1) · Children up to age 5-6 years (European / European non-Hispanic ancestry); 843 ECC-affected vs 2124 unaffected across 5 cohorts (N=2974)
The common variant rs8091366 near CHST9, KCTD1 showed suggestive (not genome-wide significant) association with ECC (Z = 4.476, p = 7.60e-6); genetic association, ungraded.
2 findings from 1 review