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Evidence found and GRADE certainty

4,410 questions · 8,901 findings · 1,091 reviews

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No studies found 1,687 · 19%GRADE not reported 1,469 · 16.5%Very low 1,969 · 22.1%Low 2,060 · 23.1%Moderate 1,302 · 14.6%High 414 · 4.7%

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Intramuscular injection of bone marrow mononuclear cells (BMMNC) vs control

All‐cause mortality ( · people with CLI who were not suitable for revascularisation and showed no improvement in response to the best standard therapy

It is very uncertain whether intramuscular injection of bone marrow mononuclear cells (BMMNC) changes all‐cause mortality ( compared with control (very low certainty).

1 finding from 1 review

Intramuscular injection of bone marrow mononuclear cells (BMMNC) vs control

Reduction in pain Various scales including VAS, PISQ; scales ranged from 0 to 4/10/100, where 0 = no pain ( · people with CLI who were not suitable for revascularisation and showed no improvement in response to the best standard therapy
1 finding from 1 review

Intramuscular injection of bone marrow mononuclear cells (BMMNC) vs control

Amputation · people with CLI who were not suitable for revascularisation and showed no improvement in response to the best standard therapy

It is very uncertain whether intramuscular injection of bone marrow mononuclear cells (BMMNC) changes incidence of amputation ( compared with control (very low certainty).

1 finding from 1 review

Intramuscular injection of bone marrow mononuclear cells (BMMNC) vs control

Angiographic analysis · people with CLI who were not suitable for revascularisation and showed no improvement in response to the best standard therapy

The review found no eligible studies for this question.

1 finding from 1 review

Intramuscular injection of bone marrow mononuclear cells (BMMNC) vs control

Increase in ABI An ABI ratio of 0.9 or less indicates PAD. Values between 0.9 and 1.0 are borderline, and above 1.0 is considered normal ( · people with CLI who were not suitable for revascularisation and showed no improvement in response to the best standard therapy
1 finding from 1 review

Intramuscular injection of bone marrow mononuclear cells (BMMNC) vs control

Complications and side effects · people with CLI who were not suitable for revascularisation and showed no improvement in response to the best standard therapy

It is very uncertain whether intramuscular injection of bone marrow mononuclear cells (BMMNC) changes side effects and complications ( compared with control (very low certainty).

1 finding from 1 review

Paracetamol vs indomethacin

Failure of PDA closure after first course of treatment (assessed by post‐treatment ECHO) · preterm infants with PDA

Paracetamol showed no clear difference in failure of PDA closure after first course of treatment (assessed by… compared with indomethacin (low certainty).

1 finding from 1 review

Prophylactic administration of paracetamol vs placebo or no intervention

Failure of PDA closure after first course of treatment (assessed by post‐treatment ECHO) · preterm infants with PDA

Prophylactic administration of paracetamol may leads to lower failure of PDA closure after first course (assessed by… compared with placebo or no intervention (low certainty).

1 finding from 1 review

Prophylactic administration of paracetamol vs placebo or no intervention

All‐cause mortality during hospital stay · preterm infants with PDA

Prophylactic administration of paracetamol showed no clear difference in all‐cause mortality during initial hospital stay (by clinical… compared with placebo or no intervention (low certainty).

1 finding from 1 review

Summary of findings: unconditional cash transfer vs no unconditional cash transfer: primary outcomes

Has used any health service in previous 1 to 12 months · children (0 to 17 years) and adults (≥ 18 years) or households

Summary of findings: unconditional cash transfer showed no clear difference in has used any health service in previous 1 to 12 months compared with no unconditional cash transfer: primary outcomes (low certainty).

1 finding from 1 review

Summary of findings: unconditional cash transfer vs no unconditional cash transfer: primary outcomes

Engages in child labour · children (0 to 17 years) and adults (≥ 18 years) or households

It is very uncertain whether summary of findings: unconditional cash transfer changes engages in child labour compared with no unconditional cash transfer: secondary outcomes (very low certainty).

1 finding from 1 review

Summary of findings: unconditional cash transfer vs no unconditional cash transfer: primary outcomes

Adult works · children (0 to 17 years) and adults (≥ 18 years) or households

It is very uncertain whether summary of findings: unconditional cash transfer changes adult works compared with no unconditional cash transfer: secondary outcomes (very low certainty).

1 finding from 1 review

Summary of findings: unconditional cash transfer vs no unconditional cash transfer: primary outcomes

Is extremely poor · children (0 to 17 years) and adults (≥ 18 years) or households

Summary of findings: unconditional cash transfer may leads to lower is extremely poor compared with no unconditional cash transfer: secondary outcomes (low certainty).

1 finding from 1 review