Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,072 questions · 4,237 findings · 447 reviews · Headline outcomes only

No studies found 946 · 22.3%GRADE not reported 257 · 6.1%Very low 1,121 · 26.5%Low 1,207 · 28.5%Moderate 568 · 13.4%High 138 · 3.3%

Intervention not reported

All‐cause mortality · children and adolescents with obesity

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Morbidity (metabolic syndrome)d · children and adolescents with obesity

It is very uncertain whether the intervention changes morbidity (metabolic syndrome)d (very low certainty).

1 finding from 1 review

Intervention not reported

Socioeconomic effects · children and adolescents with obesity

The review found no eligible studies for this question.

1 finding from 1 review

ISBCS vs DSBCS

Proportion of participants with endophthalmitis · people with bilateral age‐related cataracts (NRSs)
2 findings from 1 review

ISBCS vs DSBCS

Complications · people with bilateral age‐related cataracts (NRSs)

It is very uncertain whether ISBCS changes complications compared with DSBCS (very low certainty).

2 findings from 1 review

ISBCS vs DSBCS

Total costs per QALY · people with bilateral age‐related cataracts (NRSs)

The review found no eligible studies for this question.

2 findings from 1 review

ISBCS vs DSBCS

BCDVA · people with bilateral age‐related cataracts (NRSs)

The review found no eligible studies for this question.

2 findings from 1 review

ISBCS vs DSBCS

Patient‐reported outcome measures (PROMs) · people with bilateral age‐related cataracts (NRSs)

The review found no eligible studies for this question.

2 findings from 1 review

ISBCS vs DSBCS

Refraction NOT within 1.0 dioptres of target · people with bilateral age‐related cataracts (NRSs)

ISBCS showed no clear difference in refraction NOT within 1.0 dioptres of target compared with DSBCS (moderate certainty).

2 findings from 1 review

Timing of wound closure (immediate vs delayed)

Deep surgical site infection · adults with open long bone fractures of the upper and lower limbs

It is very uncertain whether timing of wound closure (immediate changes deep surgical site infection compared with delayed) (very low certainty).

1 finding from 1 review

Timing of wound closure (immediate vs delayed)

Delayed or non‐union (medium term) · adults with open long bone fractures of the upper and lower limbs

It is very uncertain whether timing of wound closure (immediate changes delayed union or non‐union compared with delayed) (very low certainty).

1 finding from 1 review

Timing of wound closure (immediate vs delayed)

Adverse events ‐ superficial infection · adults with open long bone fractures of the upper and lower limbs

It is very uncertain whether timing of wound closure (immediate changes adverse events ‐ superficial infection compared with delayed) (very low certainty).

1 finding from 1 review