Smoking cessation · people who smoke
Higher‐dose showed no clear difference in smoking cessation ‐ 42/44 mg versus 21/22 mg (24‐hour patches) compared with lower‐dose nicotine patch (moderate certainty).
3 findings from 1 review
RR 1.09 [0.93, 1.29]
5 studies · 1655 participants
Moderate
RR 1.19 [1, 1.41]
3 studies · 3446 participants
Moderate
RR 1.48 [1.06, 2.08]
1 study · 537 participants
Moderate
SAEs · people who smoke
Higher‐dose showed no clear difference in overall SAEs ‐ 42/44 mg versus 21/22 mg (24 hr patches) compared with lower‐dose nicotine patch (low certainty).
2 findings from 1 review
Treatment withdrawal · people who smoke
Higher‐dose may leads to higher treatment withdrawals ‐ 42/44 mg versus 21/22 mg (24‐hour patches) compared with lower‐dose nicotine patch (low certainty).
1 finding from 1 review
Treatment withdrawals ‐ 21 mg versus 14 mg (24‐hour patches) · people who smoke
Higher‐dose showed no clear difference in treatment withdrawals ‐ 21 mg versus 14 mg (24‐hour patches) compared with lower‐dose nicotine patch (low certainty).
1 finding from 1 review
Intervention not reported
Smoking cessation ‐ oral spray versus gum · people who smoke
It is very uncertain whether the intervention changes smoking cessation ‐ oral spray versus gum (very low certainty).
1 finding from 1 review
Intervention not reported
Smoking cessation ‐ oral spray versus inhaler · people who smoke
It is very uncertain whether the intervention changes smoking cessation ‐ oral spray versus inhaler (very low certainty).
1 finding from 1 review
Intervention not reported
Smoking cessation ‐ gum versus inhaler · people who smoke
It is very uncertain whether the intervention changes smoking cessation ‐ gum versus inhaler (very low certainty).
1 finding from 1 review
Intervention not reported
Overall serious adverse events · people who smoke
1 finding from 1 review
Intervention not reported
Treatment withdrawals · people who smoke
1 finding from 1 review
Physical aggression · persistent aggressive behaviour or agitation in people with schizophrenia
1 finding from 1 review
Specific behaviour ‐ agitation · persistent aggressive behaviour or agitation in people with schizophrenia
1 finding from 1 review
Adverse events: Clinically important effect · persistent aggressive behaviour or agitation in people with schizophrenia
1 finding from 1 review
Self harm ‐ frequency of self harm · persistent aggressive behaviour or agitation in people with schizophrenia
1 finding from 1 review
Mental state: clinically important change in mental state · persistent aggressive behaviour or agitation in people with schizophrenia
1 finding from 1 review
Leaving the study early · persistent aggressive behaviour or agitation in people with schizophrenia
1 finding from 1 review
Quality of life: clinically important change in quality of life · persistent aggressive behaviour or agitation in people with schizophrenia
1 finding from 1 review
Intervention not reported
Quality of life · people with a confirmed diagnosis of advanced renal cell carcinoma (RCC) and a favourable risk according to the International Metastatic…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Progression‐free survival (PFS) ‐ Network (subnet 1) included 5 pairwise comparisons ‐ Median · people with a confirmed diagnosis of advanced renal cell carcinoma (RCC) and a favourable risk according to the International Metastatic…
1 finding from 1 review
Intervention not reported
Adverse events (grade 3 to 4) · people with a confirmed diagnosis of advanced renal cell carcinoma (RCC) and a favourable risk according to the International Metastatic…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
MSKCC risk group · people with a confirmed diagnosis of advanced renal cell carcinoma (RCC) and a favourable risk according to the International Metastatic…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found