Discomfort associated with the procedure · Children with decayed primary molar teeth
Preformed crown (any material; conventional technique or Hall… probably leads to lower discomfort associated with the procedure compared with filling (any material; with or without complete carious tissue… (moderate certainty).
1 finding from 1 review
Oral pain · All patients with cancer who are receiving treatment
3 findings from 1 review
Oral pain was assessed in this subgroup but the study (Kakoei 2013) did not report details of the scale used, so the data could not be used (no usable estimate).
1 study
GRADE not reported
MD -1.93 [-2.37, -1.49]
1 study · 80 participants
Very low
MD -1.5 [-2.11, -0.89]
2 studies · 85 participants
Low
Caries increment (DFS), prevented fraction at 2.5 to 3 years · Children with permanent teeth (schoolchildren)
1 finding from 1 review
Sucking cessation (short term) · Children with a non-nutritive sucking habit (digit or pacifier)
Psychological intervention + palatal arch led to lower sucking cessation (short term) compared with psychological intervention + palatal crib; GRADE not reported.
1 finding from 1 review
Chlorhexidine mouthrinse vs Placebo or no intervention (including routine care)
Outcome not reported · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
The review found no eligible studies for this question.
1 finding from 1 review
Overall survival · People with squamous cell carcinoma of the oral cavity or oropharynx
EGFR monoclonal antibody (cetuximab or nimotuzumab) plus standard… probably leads to lower overall survival compared with standard therapy alone (radiotherapy or chemoradiotherapy) (moderate certainty).
1 finding from 1 review
Caries (lesion) progression (radiographic) · Dentate children and adults with non-cavitated proximal caries lesions extending into enamel or dentine (not pulp) in primary or permanent…
Micro-invasive treatment (proximal sealing or resin infiltration):… probably leads to lower caries (lesion) progression measured by pairwise reading of… compared with non-invasive measures (e.g. fluoride varnish, flossing/oral hygiene… (moderate certainty).
4 findings from 1 review
Show 1 more finding
OR 0.27 [0.17, 0.44]
5 studies
Moderate
Overall survival · People with squamous cell carcinoma of the oral cavity or oropharynx
2 findings from 1 review
BCG-CWP + surgery versus surgery alone: 3-year overall survival 10/10 vs 9/10; too few participants to calculate a hazard ratio (Bier 1981, 24 participants).
1 study · 24 participants
GRADE not reported
HR 0.52 [0.31, 0.87]
1 study · 201 participants
Very low
Disparities in caries across socioeconomic status (SES) · People of all ages in a community setting; the included caries studies were all in children aged 3 to 16 years
1 finding from 1 review
There is insufficient information to determine whether initiation of a water fluoridation programme results in a change in disparities in caries levels across SES. Data from 3 observational studies (participants not…
3 studies · 35399 participants
Low
Catastrophic failure of the restored tooth or restoration leading directly to extraction · People with a permanent tooth that has undergone endodontic (root canal) treatment
1 finding from 1 review
SoF 'Catastrophic failure of restoration': assumed risk (conventional filling) 0, corresponding risk (single crown) 0; no events in either group so a relative effect was not estimable; 117 participants (1 study); GRADE…
1 study · 117 participants
Very low
Requirement for general anaesthesia due to dental procedures for caries · general population
The review found no eligible studies for this question.
1 finding from 1 review
Oral mucositis (any severity) · All patients with cancer who are receiving treatment
Oral cryotherapy (ice chips, ice-cold water, ice cubes or crushed… showed no clear difference in oral mucositis (any severity) compared with control (no treatment or standard/usual oral care, e.g. saline rinse) (low certainty).
3 findings from 1 review
RR 0.59 [0.35, 1.01]
5 studies · 270 participants
Low
RR 0.61 [0.52, 0.72]
5 studies · 444 participants
Moderate
RR 0.98 [0.90, 1.07]
1 study · 122 participants
Very low
Caries in primary teeth (mean number of decayed primary teeth) · Infants (primary teeth; baseline about 9 to 15 months)
1 finding from 1 review
Number of infants with a caries increment (dmfs) · Infants (primary teeth)
Xylitol wipes (4.2 g/day) showed no clear difference in number of infants with a caries increment (dmfs) compared with control wipes (no xylitol) (low certainty).
1 finding from 1 review
Major failure · Children with decayed primary molar teeth
2 findings from 1 review
Number of days in hospital (duration of hospitalisation) · All patients with cancer who are receiving treatment
The review found no eligible studies for this question.
2 findings from 1 review
Removal of broken (fractured) instruments from the root canal · Patients of any age who received endodontic therapy and were followed up for at least 1 year after treatment
The review found no eligible studies for this question.
1 finding from 1 review
Change in proportion of caries-free children (permanent teeth) · People of all ages in a community setting; the included caries studies were all in children aged 3 to 16 years
Initiation of water fluoridation (artificial or natural) may leads to higher change in proportion of caries-free children (permanent teeth) compared with low/non-fluoridated water (0.4 ppm fluoride or less) (low certainty).
1 finding from 1 review
Caries (lesion) progression (radiographic) · Dentate children and adults with non-cavitated proximal caries lesions extending into enamel or dentine (not pulp) in primary or permanent…
1 finding from 1 review
Time to restoration failure/retreatment · Children with decayed primary molar teeth
The review found no eligible studies for this question.
1 finding from 1 review