Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,749 questions · 14,261 findings · 832 reviews

No studies found 3,655 · 25.6%GRADE not reported 2,111 · 14.8%Very low 3,646 · 25.6%Low 3,028 · 21.2%Moderate 1,501 · 10.5%High 320 · 2.2%

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Bilateral lateral rectus recession vs lateral rectus recession and medial rectus resection

Minor adverse events Defined as any adverse event within 8 weeks of surgery that does not require further intervention · people with intermittent exotropia, aged 3 to < 11 years

Bilateral lateral rectus recession showed no clear difference in minor adverse events Defined as any adverse event within 8 weeks of… compared with unilateral lateral rectus recession with medial rectus resection (low certainty).

1 finding from 1 review

Patching vs active observation

Motor alignment at near fixation Measured using PACT at 6 months · people with intermittent exotropia, aged less than 11 years

Patching showed no clear difference in motor alignment at near fixation Measured using PACT at 6 months compared with active observation (high certainty).

1 finding from 1 review

Patching vs active observation

Stereoacuity at near · people with intermittent exotropia, aged less than 11 years

Patching showed no clear difference in stereoacuity at near Measured using the Preschool Randot, Titmus… compared with active observation (low certainty).

1 finding from 1 review

Endovenous laser ablation (EVLA) vs radiofrequency ablation

Technical success · people with GSV incompetence

Endovenous laser ablation (EVLA) showed no clear difference in technical success (< 5 years) compared with radiofrequency ablation (RFA) (moderate certainty).

2 findings from 1 review

Endovenous laser ablation (EVLA) vs SFJ ligation and stripping (HL/S)

Technical success · people with GSV incompetence

Endovenous laser ablation (EVLA) may leads to higher technical success (< 5 years) compared with SFJ ligation and stripping (HL/S) (low certainty).

2 findings from 1 review

Radiofrequency ablation (RFA) vs mechanochemical ablation (MOCA)

Technical success · people with GSV incompetence

Radiofrequency ablation (RFA) showed no clear difference in technical success (< 5 years) compared with mechanochemical ablation (MOCA) (low certainty).

2 findings from 1 review

Radiofrequency ablation (RFA) vs SFJ ligation and stripping (HL/S)

Technical success · people with GSV incompetence

Radiofrequency ablation (RFA) showed no clear difference in technical success (< 5 years) compared with SFJ ligation and stripping (HL/S) (low certainty).

2 findings from 1 review