Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,710 questions · 14,842 findings · 1,394 reviews

No studies found 2,880 · 19.4%GRADE not reported 1,413 · 9.5%Very low 3,103 · 20.9%Low 3,870 · 26.1%Moderate 2,663 · 17.9%High 913 · 6.2%

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Antidepressants vs placebo

Clinical response of depression · adults with psychotic depression

It is very uncertain whether antidepressant changes clinical response of depression compared with placebo (very low certainty).

1 finding from 1 review

Antidepressant plus antipsychotic vs placebo plus antidepressant

Clinical response of depression · adults with psychotic depression

It is very uncertain whether antidepressant plus antipsychotic changes clinical response of depression compared with placebo plus antidepressant (very low certainty).

2 findings from 1 review