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Search review questions
Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
1,645 questions in 107 reviews · Wounds
current versionsNo studies 651 · 39.6%Ungraded 84 · 5.1%Very low 554 · 33.7%Low 283 · 17.2%Moderate 64 · 3.9%High 9 · 0.5%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Topical antimicrobial agent vs topical non‐antimicrobial agent Time to complete wound healing (time to event data) (6 months) Topical treatment for facial burns (2020) · Cochrane | no estimate extracted | 39 participants | Moderate |
Miscellaneous treatment vs miscellaneous treatment Change in wound surface area over time or partial wound healing · people with facial burns Topical treatment for facial burns (2020) · Cochrane | no estimate extracted | 2011 participants | Ungraded |
Miscellaneous treatment vs miscellaneous treatment Infection ( · people with facial burns Topical treatment for facial burns (2020) · Cochrane | no estimate extracted | 43 participants | Very low |
Topical antimicrobial agent vs topical non‐antimicrobial agent Time to complete wound healing (days) (until wound healing) Topical treatment for facial burns (2020) · Cochrane | no estimate extracted | 60 participants | Low |
Topical antimicrobial agent vs topical non‐antimicrobial agent Proportion of wounds completely healed within 10 days (10 days) Topical treatment for facial burns (2020) · Cochrane | RR 0.94 [0.68, 1.29] | 39 participants | Low |
Topical antimicrobial agent vs topical non‐antimicrobial agent Change in wound surface area over time or partial healing – not measured Topical treatment for facial burns (2020) · Cochrane | no estimate extracted | NR | No studies |
Topical antimicrobial agent vs topical non‐antimicrobial agent Infection (unclear Topical treatment for facial burns (2020) · Cochrane | RR 0.38 [0.12, 1.21] | 40 participants | Very low |
Topical antimicrobial vs alternative antimicrobial agent Outcomes ( · people with facial burns Topical treatment for facial burns (2020) · Cochrane | no estimate extracted | NR | No studies |
Topical antimicrobial vs alternative antimicrobial agent Time to complete wound healing · people with facial burns Topical treatment for facial burns (2020) · Cochrane | no estimate extracted | NR | No studies |
Topical antimicrobial vs alternative antimicrobial agent Proportion of wounds completely healed · people with facial burns Topical treatment for facial burns (2020) · Cochrane | no estimate extracted | NR | No studies |
2‐hourly repositioning vs 4‐hourly repositioning Pressure injury (stages 1 to 4) Short‐term · adults Repositioning for pressure injury prevention in adults (2020) · Cochrane | RR 1.06 [0.8, 1.41] | 3 studies · 1074 participants | Very low |
30° 3‐hourly tilt vs 90° tilt Patient satisfaction · adults Repositioning for pressure injury prevention in adults (2020) · Cochrane | no estimate extracted | NR | No studies |
30° 3‐hourly tilt vs 90° tilt Costs · adults Repositioning for pressure injury prevention in adults (2020) · Cochrane | no estimate extracted | NR | No studies |
30° 3‐hourly tilt vs 90° tilt Incremental costs · adults Repositioning for pressure injury prevention in adults (2020) · Cochrane | no estimate extracted | 1 study · 213 participants | Ungraded |
2‐hourly repositioning vs 4‐hourly repositioning Health‐related quality of life · adults Repositioning for pressure injury prevention in adults (2020) · Cochrane | no estimate extracted | NR | No studies |
2‐hourly repositioning vs 4‐hourly repositioning Procedural pain · adults Repositioning for pressure injury prevention in adults (2020) · Cochrane | no estimate extracted | NR | No studies |
2‐hourly repositioning vs 4‐hourly repositioning Patient satisfaction · adults Repositioning for pressure injury prevention in adults (2020) · Cochrane | no estimate extracted | NR | No studies |
2‐hourly repositioning vs 4‐hourly repositioning Costs · adults Repositioning for pressure injury prevention in adults (2020) · Cochrane | OR 4 | 1 study · 967 participants | Ungraded |
2‐hourly repositioning vs 4‐hourly repositioning Incremental costs · adults Repositioning for pressure injury prevention in adults (2020) · Cochrane | no estimate extracted | NR | No studies |
30° 3‐hourly tilt vs 90° tilt Pressure injury (stages 1 to 4) Short‐term · adults Repositioning for pressure injury prevention in adults (2020) · Cochrane | RR 0.62 [0.1, 3.97] | 2 studies · 252 participants | Very low |
30° 3‐hourly tilt vs 90° tilt Health‐related quality of life · adults Repositioning for pressure injury prevention in adults (2020) · Cochrane | no estimate extracted | NR | No studies |
30° 3‐hourly tilt vs 90° tilt Procedural pain · adults Repositioning for pressure injury prevention in adults (2020) · Cochrane | no estimate extracted | NR | No studies |
Oral nutritional supplement with 20 g protein per 200 mL bottle, 1 kcal/mL, nutritional supplement with added vitamins, minerals and trace elements vs placebo Ulcer healing (absolute change in individual parameters of ulcer dimensions over time) · people with diabetes and foot ulcers Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane | no estimate extracted | NR | No studies |
Arginine, glutamine and β‐hydroxy‐β‐methylbutyrate supplement vs placebo Adverse events · people with diabetes and foot ulcers Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane | no estimate extracted | NR | No studies |
Arginine, glutamine and β‐hydroxy‐β‐methylbutyrate supplement vs placebo Development of any new foot ulcers · people with diabetes and foot ulcers Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane | RR 1.04 | 1 study · 270 participants | Very low |
Arginine, glutamine and β‐hydroxy‐β‐methylbutyrate supplement vs placebo Amputation rate · people with diabetes and foot ulcers Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane | RR 0.66 [0.16, 2.69] | 1 study · 270 participants | Very low |
220 mg zinc sulphate supplement containing 50 mg elemental zinc vs placebo Ulcer healing (absolute change in individual parameters of ulcer dimensions over time: mean (SD) cm wound length reduction) · people with diabetes and foot ulcers Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane | no estimate extracted | 1 study · 60 participants | Very low |
220 mg zinc sulphate supplement containing 50 mg elemental zinc vs placebo Ulcer healing (absolute change in individual parameters of ulcer dimensions over time: mean (SD) cm wound depth reduction) · people with diabetes and foot ulcers Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane | no estimate extracted | 1 study · 60 participants | Very low |
220 mg zinc sulphate supplement containing 50 mg elemental zinc vs placebo Ulcer healing (absolute change in individual parameters of ulcer dimensions over time: mean (SD) cm wound width reduction) · people with diabetes and foot ulcers Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane | no estimate extracted | 1 study · 60 participants | Very low |
220 mg zinc sulphate supplement containing 50 mg elemental zinc vs placebo Ulcer healing (proportion of ulcers healed) · people with diabetes and foot ulcers Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane | no estimate extracted | NR | No studies |
220 mg zinc sulphate supplement containing 50 mg elemental zinc vs placebo Quality of life · people with diabetes and foot ulcers Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane | no estimate extracted | NR | No studies |
220 mg zinc sulphate supplement containing 50 mg elemental zinc vs placebo Adverse events · people with diabetes and foot ulcers Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane | no estimate extracted | NR | No studies |
220 mg zinc sulphate supplement containing 50 mg elemental zinc vs placebo Development of any new foot ulcers · people with diabetes and foot ulcers Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane | no estimate extracted | NR | No studies |
Oral nutritional supplement with 20 g protein per 200 mL bottle, 1 kcal/mL, nutritional supplement with added vitamins, minerals and trace elements vs placebo Ulcer healing (proportion of ulcers healed) · people with diabetes and foot ulcers Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane | RR 0.8 [0.42, 1.53] | 1 study · 53 participants | Very low |
220 mg zinc sulphate supplement containing 50 mg elemental zinc vs placebo Amputation rate · people with diabetes and foot ulcers Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane | no estimate extracted | NR | No studies |
250 mg magnesium oxide supplement vs placebo Ulcer healing (absolute change in individual parameters of ulcer dimensions over time: mean (SD) cm wound length reduction) · people with diabetes and foot ulcers Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane | no estimate extracted | 1 study · 70 participants | Very low |
250 mg magnesium oxide supplement vs placebo Ulcer healing (absolute change in individual parameters of ulcer dimensions over time: mean (SD) cm wound depth reduction) · people with diabetes and foot ulcers Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane | no estimate extracted | 1 study · 70 participants | Very low |
250 mg magnesium oxide supplement vs placebo Ulcer healing (absolute change in individual parameters of ulcer dimensions over time: mean (SD) cm wound width reduction) · people with diabetes and foot ulcers Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane | no estimate extracted | 1 study · 70 participants | Very low |
250 mg magnesium oxide supplement vs placebo Ulcer healing (proportion of ulcers healed) · people with diabetes and foot ulcers Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane | no estimate extracted | NR | No studies |
250 mg magnesium oxide supplement vs placebo Quality of life · people with diabetes and foot ulcers Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane | no estimate extracted | NR | No studies |
250 mg magnesium oxide supplement vs placebo Adverse events · people with diabetes and foot ulcers Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane | no estimate extracted | NR | No studies |
250 mg magnesium oxide supplement vs placebo Development of any new foot ulcers · people with diabetes and foot ulcers Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane | no estimate extracted | NR | No studies |
250 mg magnesium oxide supplement vs placebo Amputation rate · people with diabetes and foot ulcers Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane | no estimate extracted | NR | No studies |
1000 mg/day omega‐3 fatty acid from flaxseed oil supplement vs placebo Ulcer healing (absolute change in individual parameters of ulcer dimensions over time: mean (SD) cm wound length reduction) · people with diabetes and foot ulcers Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane | no estimate extracted | 1 study · 60 participants | Very low |
Oral nutritional supplement with 20 g protein per 200 mL bottle, 1 kcal/mL, nutritional supplement with added vitamins, minerals and trace elements vs placebo Quality of life · people with diabetes and foot ulcers Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane | no estimate extracted | NR | No studies |
1000 mg/day omega‐3 fatty acid from flaxseed oil supplement vs placebo Ulcer healing (absolute change in individual parameters of ulcer dimensions over time: mean (SD) cm wound depth reduction) · people with diabetes and foot ulcers Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane | no estimate extracted | 1 study · 60 participants | Very low |
1000 mg/day omega‐3 fatty acid from flaxseed oil supplement vs placebo Ulcer healing (absolute change in individual parameters of ulcer dimensions over time: mean (SD) cm wound width reduction) · people with diabetes and foot ulcers Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane | no estimate extracted | 1 study · 60 participants | Very low |
1000 mg/day omega‐3 fatty acid from flaxseed oil supplement vs placebo Ulcer healing (proportion of ulcers healed) · people with diabetes and foot ulcers Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane | no estimate extracted | NR | No studies |
1000 mg/day omega‐3 fatty acid from flaxseed oil supplement vs placebo Quality of life · people with diabetes and foot ulcers Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane | no estimate extracted | NR | No studies |
1000 mg/day omega‐3 fatty acid from flaxseed oil supplement vs placebo Adverse events · people with diabetes and foot ulcers Nutritional interventions for treating foot ulcers in people with diabetes (2020) · Cochrane | no estimate extracted | NR | No studies |