Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

462 questions · 474 findings · 56 reviews · Eyes and Vision

No studies found 147 · 31%GRADE not reported 15 · 3.2%Very low 89 · 18.8%Low 157 · 33.1%Moderate 52 · 11%High 14 · 3%

Regular‐dose postoperative 5‐Fluorouracil vs control

Complications ‐ wound leak ‐ high risk of failure · participants with glaucoma surgery

Regular‐dose postoperative 5‐Fluorouracil probably leads to higher complications ‐ wound leak ‐ high risk of failure compared with control (moderate certainty).

1 finding from 1 review

Intervention not reported

Reported complications Laser capsulotomies for posterior capsule opacification (PCO) · Participants over age of 21 years undergoing cataract surgery

The intervention may leads to higher reported complications Laser capsulotomies for posterior capsule… (low certainty).

1 finding from 1 review

Intervention not reported

Surgical failure (intraocular pressure >21mmHg) ( · patients with glaucoma surgery

The intervention probably leads to lower surgical failure (intraocular pressure >21mmHg) ( (moderate certainty).

1 finding from 1 review

Intervention not reported

Intraocular pressure ( · patients with glaucoma surgery
1 finding from 1 review

Intervention not reported

Adverse effect: cataract · patients with glaucoma surgery

The intervention showed no clear difference in adverse effect: cataract (moderate certainty).

1 finding from 1 review

Intervention not reported

Trabeculectomy failure at 12 months · People undergoing trabeculectomy surgery with glaucoma

The intervention probably leads to lower trabeculectomy failure at 12 months (moderate certainty).

1 finding from 1 review

Intervention not reported

mean intraocular pressure mmHg at 12 months · People undergoing trabeculectomy surgery with glaucoma
1 finding from 1 review

Intervention not reported

complications wound leak by 12 months · People undergoing trabeculectomy surgery with glaucoma

The intervention showed no clear difference in complications wound leak by 12 months (low certainty).

1 finding from 1 review

Intervention not reported

complications hypotony occurring up to 12 months · People undergoing trabeculectomy surgery with glaucoma

The intervention showed no clear difference in complications hypotony occurring up to 12 months (low certainty).

1 finding from 1 review

Intervention not reported

complications shallow anterior chamber occurring within 12 months · People undergoing trabeculectomy surgery with glaucoma

The intervention showed no clear difference in complications shallow anterior chamber occurring within 12 months (low certainty).

1 finding from 1 review

Intervention not reported

cataract formation by 12 months · People undergoing trabeculectomy surgery with glaucoma

The intervention showed no clear difference in cataract formation by 12 months (moderate certainty).

1 finding from 1 review

Botulinum toxin vs surgery

Improved or corrected strabismusa at 6 or 12 months · adults and children with strabismus

Botulinum toxin may leads to lower improved or corrected strabismusa at 6 or 12 months compared with surgery (low certainty).

1 finding from 1 review

Botulinum toxin vs surgery

Proportion of participants who achieved binocular single vision at 6 or 12 months · adults and children with strabismus

Botulinum toxin showed no clear difference in proportion of participants who achieved binocular single vision at 6… compared with surgery (low certainty).

1 finding from 1 review