Adverse events · Adults with cancer receiving treatment
1 finding from 1 review
Interruptions to cancer treatment (radiotherapy breaks longer than two days) · Adults with cancer receiving treatment
Epidermal growth factor (EGF), oral spray showed no clear difference in interruptions to cancer treatment (radiotherapy breaks longer than… compared with placebo; GRADE not reported.
1 finding from 1 review
Normalcy of diet (total parenteral nutrition) · Adults with cancer receiving treatment
Epidermal growth factor (EGF), oral spray showed no clear difference in normalcy of diet (total parenteral nutrition) compared with placebo; GRADE not reported.
1 finding from 1 review
Adverse events · Adults receiving chemotherapy alone for colorectal cancer
1 finding from 1 review
Caries (DMFT) and enamel defects · Preterm children (about 8 years old) in the United Arab Emirates (Dubai)
One study found preterm children had higher DMFT and a fourfold higher prevalence of enamel defects than full-term children (narrative synthesis; not GRADE-rated).
1 finding from 1 review
Alshehhi et al. (Dubai) reported a significantly higher mean DMFT (1.00 vs 0.38) and a 4-times higher prevalence of enamel defects (58.15% vs 24.2%; OR 4.33, 95% CI 2.01-9.36) in preterm vs full-term children, highest…
1 study
GRADE not reported
Oral cytology (e.g. OralCDx brush biopsy, CytID) vs Reference standard: examination and clinical evaluation by a physician/clinician with specialist knowledge or training (long-term follow-up accepted for those screened negative)
Outcome not reported · Apparently healthy adults not reporting symptoms of OPMD or OSCC, attending an organised screening or surveillance programme, or screened…
The review found no eligible studies for this question.
1 finding from 1 review
Probing pocket depth · Children or adults (fit and healthy, or with a well-defined medical condition)
1 finding from 1 review
Dental caries · Children or adults (fit and healthy, or with a well-defined medical condition)
It is very uncertain whether any form of one-to-one oral hygiene advice (OHA) changes dental caries compared with no OHA (very low certainty).
1 finding from 1 review
SoF: 1 study in adults reported only 'small and statistically insignificant changes' but no usable data; the other study on infants provided evidence of a benefit for OHA at 8 and 12 months but not at 4 months.…
2 studies · 244 participants
Very low
Gingivitis · Children or adults (fit and healthy, or with a well-defined medical condition)
It is very uncertain whether any form of one-to-one oral hygiene advice (OHA) changes periodontal health: gingivitis compared with no OHA (very low certainty).
1 finding from 1 review
SoF: 1 small study in adults had contradictory results at 3 and 6 months; the other study in adults showed evidence of a benefit for OHA at all time points (12, 24, 36 months). Results: Hetland 1982 MD 0.25 (0.05 to…
2 studies · 235 participants
Very low
Patient-reported changes in knowledge, attitudes and quality of life · Children or adults (fit and healthy, or with a well-defined medical condition)
1 finding from 1 review
Hoogstraten 1983 (dental knowledge, attitude, behaviour, fear of dental treatment) and Memarpour 2016 (parents' knowledge and performance regarding oral health); measured, not synthesised or GRADE-rated.
2 studies
GRADE not reported
Adverse events · Children or adults (fit and healthy, or with a well-defined medical condition)
1 finding from 1 review
Plaque · Children or adults (fit and healthy, or with a well-defined medical condition)
Any form of one-to-one oral hygiene advice (OHA) showed no clear difference in periodontal health: plaque levels compared with no OHA (low certainty).
1 finding from 1 review
SoF: Both studies at all time points consistently showed a benefit in plaque reduction for OHA. Results: Hetland 1982 MD -0.41 (-0.54 to -0.28) at 3mo, -0.44 (-0.56 to -0.32) at 6mo; Hugoson 2007 MD -13.00 (-19.89 to…
2 studies · 235 participants
Low
Reduction of apnoea to less than one episode per hour (polysomnography) · Children with obstructive sleep apnoea (aged 15 years or younger)
1 finding from 1 review
Daytime symptom: thirstiness in the morning (questionnaire) · Children with obstructive sleep apnoea (aged 15 years or younger)
Oral appliance or functional orthopaedic appliance showed no clear difference in daytime symptom: thirstiness in the morning (questionnaire) compared with placebo or no treatment; GRADE not reported.
1 finding from 1 review
Signs and symptoms of atypical swallowing and speech production disturbances · Children with obstructive sleep apnoea (aged 15 years or younger)
The review found no eligible studies for this question.
1 finding from 1 review
Reduction of apnoea episodes (apnoea-hypopnoea index) · Children with obstructive sleep apnoea (aged 15 years or younger)
It is very uncertain whether oral appliance or functional orthopaedic appliance changes reduction of apnoea episodes (apnoea-hypopnoea index) compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Nocturnal symptom: nightmares (questionnaire) · Children with obstructive sleep apnoea (aged 15 years or younger)
Oral appliance or functional orthopaedic appliance showed no clear difference in nocturnal symptom: nightmares (questionnaire) compared with placebo or no treatment; GRADE not reported.
1 finding from 1 review
Alteration of growth pattern (cephalometric data or facial analysis) · Children with obstructive sleep apnoea (aged 15 years or younger)
The review found no eligible studies for this question.
1 finding from 1 review
Tiredness · Children with obstructive sleep apnoea (aged 15 years or younger)
It is very uncertain whether oral appliance or functional orthopaedic appliance changes daytime symptom: tiredness (Brouillette questionnaire) compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Nocturnal symptom: habitual snoring (questionnaire) · Children with obstructive sleep apnoea (aged 15 years or younger)
It is very uncertain whether oral appliance or functional orthopaedic appliance changes nocturnal symptom: habitual snoring (questionnaire) compared with placebo or no treatment (very low certainty).
1 finding from 1 review