Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,245 questions · 1,274 findings · 321 reviews

No studies found 247 · 19.4%GRADE not reported 195 · 15.3%Very low 372 · 29.2%Low 282 · 22.1%Moderate 141 · 11.1%High 37 · 2.9%

Intervention not reported

Use of one or more red blood cell transfusions (low and high dose of EPO) during initial hospital stay · preterm infants with low birth weight

It is very uncertain whether the intervention changes use of one or more red blood cell transfusions (low and high dose of… (very low certainty).

1 finding from 1 review

Brain‐derived neurotrophic factor vs placebo

Participants with 1 or more serious adverse events · patients with Guillain‐Barré syndrome

It is very uncertain whether brain‐derived neurotrophic factor changes participants with 1 or more serious adverse events compared with placebo (very low certainty).

1 finding from 1 review

Cerebrospinal fluid filtration vs plasma exchange

Participants with 1 or more serious adverse events · patients with Guillain‐Barré syndrome

It is very uncertain whether cerebrospinal fluid filtration changes participants with 1 or more serious adverse events compared with plasma exchange (very low certainty).

1 finding from 1 review

Eculizumab vs placebo

Participants with 1 or more serious adverse events · adults with severe Guillain‐Barré syndrome (GBS disability score > 2), within 2 weeks form onset

Eculizumab showed no clear difference in participants with 1 or more serious adverse events compared with placebo (low certainty).

1 finding from 1 review

Interferon beta‐1a vs placebo

Participants with 1 or more serious adverse events · patients with Guillain‐Barré syndrome

It is very uncertain whether interferon beta‐1a changes participants with 1 or more serious adverse events compared with placebo (very low certainty).

1 finding from 1 review

CBT vs no treatment or treatment

Victim empathy: attitudes to women Measured by: Attitude Towards Women Scale (15 items; scores range from 0 to 45; higher scores indicate more egalitarian attitudes towards women) · young people (aged 10 to 18 years old) with harmful sexual behaviour
1 finding from 1 review

Nicotine replacement therapy vs control

Biochemically validated smoking cessation at the latest point in pregnancy (20 weeks' gestation or more) · Pregnant women who smoke

Nicotine replacement therapy may leads to higher biochemically validated smoking cessation at the latest point in… compared with control (low certainty).

1 finding from 1 review

Bupropion vs control

Biochemically validated smoking cessation at the latest point in pregnancy (20 weeks' gestation or more) · Pregnant women who smoke

Bupropion showed no clear difference in biochemically validated smoking cessation at the latest point in… compared with control (low certainty).

1 finding from 1 review