Methadone vs placebo
Deaths · adults with chronic neuropathic pain
1 finding from 1 review
- no estimate extractedStudies not reportedVery low
Findings
What do systematic reviews say?
4,815 questions · 6,211 findings · 638 reviews · Headline outcomes only
No studies found 1,052 · 16.9%GRADE not reported 441 · 7.1%Very low 1,700 · 27.4%Low 1,651 · 26.6%Moderate 1,070 · 17.2%High 297 · 4.8%
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Methadone vs placebo
CI: Confidence interval · adults with chronic neuropathic pain
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Statin plus metformin vs metformin
Improvement in acne severity · women with polycystic ovary syndrome not actively trying to conceive
1 finding from 1 review
- Statins for women with polycystic ovary syndrome not actively trying to conceive 2023 · Cochrane Headline outcomes onlyno estimate extracted1 study · 69 participantsVery low
Statin plus metformin vs metformin
Improvement in testosterone level (nmol/L) after 6 months' treatment · women with polycystic ovary syndrome not actively trying to conceive
1 finding from 1 review
- Statins for women with polycystic ovary syndrome not actively trying to conceive 2023 · Cochrane Headline outcomes onlyno estimate extracted1 study · 69 participantsVery low
Statin plus metformin vs metformin
Adverse effects · women with polycystic ovary syndrome not actively trying to conceive
1 finding from 1 review
- Statins for women with polycystic ovary syndrome not actively trying to conceive 2023 · Cochrane Headline outcomes onlyno estimate extracted2011 participantsGRADE not reported
Statin plus metformin vs metformin
Resumption of menstrual regularity · women with polycystic ovary syndrome not actively trying to conceive
1 finding from 1 review
- Statins for women with polycystic ovary syndrome not actively trying to conceive 2023 · Cochrane Headline outcomes onlyno estimate extracted1 study · 69 participantsVery low
Statin plus metformin vs metformin
Resumption of spontaneous ovulation · women with polycystic ovary syndrome not actively trying to conceive
1 finding from 1 review
- Statins for women with polycystic ovary syndrome not actively trying to conceive 2023 · Cochrane Headline outcomes onlyno estimate extracted2011 participantsGRADE not reported
Statin plus metformin vs metformin
Clinician's assessment of improvement of hirsutism Ferriman‐Gallwey score Scale from: 0 to 36 · women with polycystic ovary syndrome not actively trying to conceive
1 finding from 1 review
- Statins for women with polycystic ovary syndrome not actively trying to conceive 2023 · Cochrane Headline outcomes onlyno estimate extracted1 study · 69 participantsVery low
Cerebral NIRS oximetry vs no cerebral NIRS oximetry
All‐cause mortality · patients with preventing morbidity and mortality in very preterm infants
Cerebral NIRS oximetry showed no clear difference in all‐cause mortality compared with no cerebral NIRS oximetry (low certainty).
1 finding from 1 review
- Cerebral near‐infrared spectroscopy monitoring for prevention of brain injury in very preterm infants 2017 · Cochrane Headline outcomes onlyRR 0.5 [0.29, 1]1 study · 166 participantsLow
Cerebral NIRS oximetry vs no cerebral NIRS oximetry
Intraventricular haemorrhage, Papile grade 3/4 · patients with preventing morbidity and mortality in very preterm infants
It is very uncertain whether cerebral NIRS oximetry changes intraventricular haemorrhage grade III or IV compared with no cerebral NIRS oximetry (very low certainty).
1 finding from 1 review
- Cerebral near‐infrared spectroscopy monitoring for prevention of brain injury in very preterm infants 2017 · Cochrane Headline outcomes onlyRR 0.57 [0.25, 1.31]1 study · 166 participantsVery low
Cerebral NIRS oximetry vs no cerebral NIRS oximetry
Cystic periventricular leukomalacia (diagnosed by cranial ultrasound) · patients with preventing morbidity and mortality in very preterm infants
1 finding from 1 review
- Cerebral near‐infrared spectroscopy monitoring for prevention of brain injury in very preterm infants 2017 · Cochrane Headline outcomes onlyno estimate extracted1 study · 166 participantsVery low
Cerebral NIRS oximetry vs no cerebral NIRS oximetry
Patent ductus arteriosus · patients with preventing morbidity and mortality in very preterm infants
It is very uncertain whether cerebral NIRS oximetry changes patent ductus arteriosus compared with no cerebral NIRS oximetry (very low certainty).
1 finding from 1 review
- Cerebral near‐infrared spectroscopy monitoring for prevention of brain injury in very preterm infants 2017 · Cochrane Headline outcomes onlyRR 1.96 [0.94, 4.08]1 study · 166 participantsVery low
Cerebral NIRS oximetry vs no cerebral NIRS oximetry
Oxygen requirement at 36 weeks' postmenstrual age · patients with preventing morbidity and mortality in very preterm infants
It is very uncertain whether cerebral NIRS oximetry changes chronic lung disease (oxygen supplementation at 36 weeks'… compared with no cerebral NIRS oximetry (very low certainty).
1 finding from 1 review
- Cerebral near‐infrared spectroscopy monitoring for prevention of brain injury in very preterm infants 2017 · Cochrane Headline outcomes onlyRR 1.27 [0.94, 1.5]1 study · 132 participantsVery low
Cerebral NIRS oximetry vs no cerebral NIRS oximetry
Proven necrotising enterocolitis (Bell's stage II or III) · patients with preventing morbidity and mortality in very preterm infants
It is very uncertain whether cerebral NIRS oximetry changes proven necrotising enterocolitis (Bell's stage II or III) compared with no cerebral NIRS oximetry (very low certainty).
1 finding from 1 review
- Cerebral near‐infrared spectroscopy monitoring for prevention of brain injury in very preterm infants 2017 · Cochrane Headline outcomes onlyRR 0.83 [0.33, 1.94]1 study · 166 participantsVery low
Cerebral NIRS oximetry vs no cerebral NIRS oximetry
Retinopathy of prematurity, any or severe (stage ≥ III) · patients with preventing morbidity and mortality in very preterm infants
It is very uncertain whether cerebral NIRS oximetry changes retinopathy of prematurity, any or severe (stage ≥ III) compared with no cerebral NIRS oximetry (very low certainty).
1 finding from 1 review
- Cerebral near‐infrared spectroscopy monitoring for prevention of brain injury in very preterm infants 2017 · Cochrane Headline outcomes onlyRR 1.64 [0.75, 3]1 study · 166 participantsVery low
Cerebral NIRS oximetry vs no cerebral NIRS oximetry
Other adverse effects · patients with preventing morbidity and mortality in very preterm infants
1 finding from 1 review
- Cerebral near‐infrared spectroscopy monitoring for prevention of brain injury in very preterm infants 2017 · Cochrane Headline outcomes onlyno estimate extracted1 study · 166 participantsVery low
Methotrexate vs placebo
OutcomesTime frame of absolute effects · children and young people with JIA
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Methotrexate vs alternative disease‐modifying antirheumatic drugs
OutcomesTime frame of absolute effects · children and young people with JIA
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Methotrexate vs alternative disease‐modifying antirheumatic drugs
Treatment responsea · children and young people with JIA
Methotrexate showed no clear difference in treatment responsea(4 months) compared with alternative disease‐modifying antirheumatic drugs (low certainty).
1 finding from 1 review
- RR 1.4 [0.93, 2.1]1 study · 94 participantsLow
Methotrexate vs alternative disease‐modifying antirheumatic drugs
Sustained clinically inactive diseasec · children and young people with JIA
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found