Findings

What do systematic reviews say?

4,756 questions · 11,779 findings · 747 reviews · Headline outcomes only

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No studies found 3,205 · 27.2%GRADE not reported 628 · 5.3%Very low 3,261 · 27.7%Low 2,913 · 24.7%Moderate 1,453 · 12.3%High 319 · 2.7%

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Pharmacological interventions vs placebo

Cholestyramine 0 to 3 severity scale · uraemic pruritus

1 finding from 1 review

Interventions for itch in people with advanced chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 15 participants
Low

Summary of findings ‐ DVD plus information booklet vs information booklet alone

Mood or personal well‐being · adults and children with hemophilia

The review found no eligible studies for this question.

1 finding from 1 review

Psychological interventions for people with hemophilia 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings ‐ DVD plus information booklet vs information booklet alone

Coping strategies · adults and children with hemophilia

1 finding from 1 review

Psychological interventions for people with hemophilia 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 108 participants
Low

Summary of findings ‐ DVD plus information booklet vs information booklet alone

QoL · adults and children with hemophilia

1 finding from 1 review

Psychological interventions for people with hemophilia 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 108 participants
Low

Summary of findings ‐ DVD plus information booklet vs information booklet alone

Compliance or adherence to the trial intervention (including satisfaction): use of intervention at least once · adults and children with hemophilia

Summary of findings ‐ DVD plus information booklet showed no clear difference in compliance or adherence to the trial intervention (including… compared with information booklet alone (low certainty).

1 finding from 1 review

Psychological interventions for people with hemophilia 2020 · Cochrane Headline outcomes only
RR 1.02 [0.81, 1.28]
1 study · 108 participants
Low

Summary of findings ‐ DVD plus information booklet vs information booklet alone

Physical health: pain intensity (VAS post‐treatment scores) · adults and children with hemophilia

1 finding from 1 review

Psychological interventions for people with hemophilia 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 108 participants
Low

Summary of findings ‐ DVD plus information booklet vs information booklet alone

Cost of psychological intervention · adults and children with hemophilia

The review found no eligible studies for this question.

1 finding from 1 review

Psychological interventions for people with hemophilia 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings ‐ DVD plus information booklet vs information booklet alone

Family adjustment · adults and children with hemophilia

The review found no eligible studies for this question.

1 finding from 1 review

Psychological interventions for people with hemophilia 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Immunomodulatory interventions vs placebo

Seizure freedom · people with focal epilepsy

The review found no eligible studies for this question.

1 finding from 1 review

Immunomodulatory interventions for focal epilepsy 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Immunomodulatory interventions vs placebo

50% or greater reduction in seizure frequency · people with focal epilepsy

Immunomodulatory interventions probably leads to higher 50% or greater reduction in seizure frequency ‐ ITT analysis compared with placebo (moderate certainty).

1 finding from 1 review

Immunomodulatory interventions for focal epilepsy 2023 · Cochrane Headline outcomes only
RR 2.3
3 studies · 172 participants
Moderate

Immunomodulatory interventions vs placebo

Adverse events of glucocorticoids and immunosuppressive drugs · people with focal epilepsy

Immunomodulatory interventions may leads to higher adverse events of glucocorticoids and immunosuppressive drugs compared with placebo (low certainty).

1 finding from 1 review

Immunomodulatory interventions for focal epilepsy 2023 · Cochrane Headline outcomes only
RR 1.16
1 study · 66 participants
Low

Immunomodulatory interventions vs placebo

Treatment withdrawal · people with focal epilepsy

Immunomodulatory interventions may leads to higher treatment withdrawal compared with placebo (low certainty).

1 finding from 1 review

Immunomodulatory interventions for focal epilepsy 2023 · Cochrane Headline outcomes only
RR 1.04
3 studies · 172 participants
Low

Immunomodulatory interventions vs placebo

Allergic reaction · people with focal epilepsy

The review found no eligible studies for this question.

1 finding from 1 review

Immunomodulatory interventions for focal epilepsy 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Immunomodulatory interventions vs placebo

Cognitive effects · people with focal epilepsy

The review found no eligible studies for this question.

1 finding from 1 review

Immunomodulatory interventions for focal epilepsy 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Immunomodulatory interventions vs placebo

Quality of life · people with focal epilepsy

The review found no eligible studies for this question.

1 finding from 1 review

Immunomodulatory interventions for focal epilepsy 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Psychosocial interventions vs control intervention

Frequency of alcohol misuse 6 months · Parents who use substances

1 finding from 1 review

Effectiveness of psychosocial interventions for reducing parental substance misuse 2021 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 475 participants
Moderate

Psychosocial interventions vs control intervention

Frequency of alcohol misuse 12 months · Parents who use substances

1 finding from 1 review

Effectiveness of psychosocial interventions for reducing parental substance misuse 2021 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 366 participants
Moderate

Psychosocial interventions vs control intervention

Frequency of drug use 12 months · Parents who use substances

2 findings from 1 review

Effectiveness of psychosocial interventions for reducing parental substance misuse 2021 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 625 participants
Moderate
Effectiveness of psychosocial interventions for reducing parental substance misuse 2021 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 514 participants
Moderate

Oral care interventions (nurse-assisted toothbrushing, oral and pharyngeal cavity rinse, decontamination with antibiotics or antiseptics) vs usual care

Plaque · people with stroke

1 finding from 1 review

Interventions for improving oral health in people after stroke 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 83 participants
Very low

Oral care interventions (nurse-assisted toothbrushing, oral and pharyngeal cavity rinse, decontamination with antibiotics or antiseptics) vs usual care

Denture plaque · people with stroke

1 finding from 1 review

Interventions for improving oral health in people after stroke 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 38 participants
Low