Sleep disturbances: number of participants with insomnia · chronic pruritus of unknown origin
It is very uncertain whether serlopitant 0.25 mg changes sleep disturbances: number of participants with insomnia compared with placebo (very low certainty).
1 finding from 1 review
Depression · chronic pruritus of unknown origin
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Patient satisfaction · chronic pruritus of unknown origin
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · chronic pruritus of unknown origin
It is very uncertain whether serlopitant 5 mg changes adverse events compared with placebo (very low certainty).
1 finding from 1 review
Health‐related quality of life · chronic pruritus of unknown origin
1 finding from 1 review
Sleep disturbances: number of participants with insomnia · chronic pruritus of unknown origin
It is very uncertain whether serlopitant 5 mg changes sleep disturbances: number of participants with insomnia compared with placebo (very low certainty).
1 finding from 1 review
Depression · chronic pruritus of unknown origin
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Patient satisfaction · chronic pruritus of unknown origin
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Pruritus · chronic pruritus of unknown origin
Serlopitant 1 mg showed no clear difference in patient‐reported pruritus intensity compared with placebo (low certainty).
1 finding from 1 review
Adverse events · chronic pruritus of unknown origin
It is very uncertain whether serlopitant 1 mg changes adverse events compared with placebo (very low certainty).
1 finding from 1 review
Health‐related quality of life · chronic pruritus of unknown origin
1 finding from 1 review
Global outcome (good or excellent improvement in symptoms or signs, or both) · people with eczema
Topical steroid plus topical antibiotic showed no clear difference in global outcome (good or excellent improvement in symptoms or signs,… compared with topical steroid (low certainty).
1 finding from 1 review
Withdrawals due to adverse events · people with atopic dermatitis
1 finding from 1 review
Minor adverse events not leading to withdrawal of treatment · people with atopic dermatitis
1 finding from 1 review
Microbiology Emergence of resistant organisms · people with atopic dermatitis
1 finding from 1 review
Global change in composite ratings scale EASI ranges from 0 to 72 with higher values indicating greater severity. · people with atopic dermatitis
1 finding from 1 review
No of participants in whom S. aureus was isolated · people with atopic dermatitis
Oral antibiotic showed no clear difference in no of participants in whom S. aureus was isolated compared with placebo (low certainty).
1 finding from 1 review
Global outcome (good or excellent improvement in symptoms or signs, or both) · people with atopic dermatitis
Bleach bath showed no clear difference in global outcome (good or excellent improvement in symptoms or signs,… compared with placebo or bath emollient (low certainty).
1 finding from 1 review
Change from baseline in quality of life CDLQI ranges from 0 to 30 with higher values indicating more impaired quality of life. · people with atopic dermatitis
1 finding from 1 review
Withdrawals due to adverse events · people with atopic dermatitis
1 finding from 1 review