Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

503 questions · 503 findings · 29 reviews · Anaesthesia

No studies found 74 · 14.7%GRADE not reported 154 · 30.6%Very low 119 · 23.7%Low 105 · 20.9%Moderate 37 · 7.4%High 14 · 2.8%

Intervention not reported

Total studies: 208 RCTs Total participants: 42,445 Number of treatments: 53 Geometry of the network** · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and combination…
1 finding from 1 review

Cuffed vs uncuffed tubes

Postextubation stridor (defined as any inspiratory sound or persistent barking, or presence of sternal or intercostal retractions postextubation) · Children up to eight years undergoing general anaesthesia

It is very uncertain whether cuffed changes postextubation stridor (defined as any inspiratory sound or… compared with uncuffed tubes (very low certainty).

1 finding from 1 review

Cuffed vs uncuffed tubes

Need for ETT exchange (defined as more than one attempt to arrive at the final endotracheal tube size) · Children up to eight years undergoing general anaesthesia

It is very uncertain whether cuffed changes need for ETT exchange (defined as more than one attempt to arrive at… compared with uncuffed tubes (very low certainty).

1 finding from 1 review

Cuffed vs uncuffed tubes

Need for tracheal re‐intubation for postoperative stridor (defined as the need to re‐intubate to assure oxygenation to deal with postextubation stridor) · Children up to eight years undergoing general anaesthesia

It is very uncertain whether cuffed changes need for tracheal re‐intubation for postoperative stridor (defined… compared with uncuffed tubes (very low certainty).

1 finding from 1 review

Cuffed vs uncuffed tubes

Need for epinephrine to treat stridor (defined as the need to use epinephrine to treat postextubation stridor) · Children up to eight years undergoing general anaesthesia

It is very uncertain whether cuffed changes need for epinephrine to treat stridor (defined as the need to use… compared with uncuffed tubes (very low certainty).

1 finding from 1 review

Cuffed vs uncuffed tubes

Need for intensive care unit (ICU) admission to treat post extubation stridor (as defined by the trial authors) · Children up to eight years undergoing general anaesthesia

It is very uncertain whether cuffed changes need for intensive care unit (ICU) admission to treat post… compared with uncuffed tubes (very low certainty).

1 finding from 1 review