Adjunctive antioxidants for schizophrenia showed no clear difference in leaving the study early, short term compared with placebo (moderate certainty).
Adjunct cognitive behavioural therapy showed no clear difference in adverse event: Leaving the study early compared with adjunct supportive psychotherapy (moderate certainty).
Haloperidol showed no clear difference in leaving the study early due to any reason as a measure of overall… compared with first‐generation antipsychotics (low certainty).
It is very uncertain whether haloperidol changes leaving the study early due to adverse events as a measure of… compared with first‐generation antipsychotics (very low certainty).
It is very uncertain whether haloperidol changes leaving the study early due to any reason as a measure of overall… compared with first‐generation antipsychotics (very low certainty).
Antiepileptic drugs may leads to lower early seizures Count of events compared with placebo or standard care (low certainty).
Anti‐epileptic drugs showed no clear difference in early seizure Counts of events compared with other anti‐epileptic drugs (low certainty).
Neuroprotective agent showed no clear difference in early seizure Count of events compared with placebo (low certainty).
SPECIALISED TEAM probably leads to lower compliance with treatment ‐ treatment stopped in spite of need ‐ by… compared with STANDARD CARE (moderate certainty).
SPECIALISED TEAM showed no clear difference in compliance with treatment ‐ treatment stopped in spite of need ‐ by… compared with STANDARD CARE (moderate certainty).
Beta‐blockers showed no clear difference in global state: 1. Leaving the study early ‐ Short term compared with placebo (low certainty).
OFS leads to lower overall survival (OS) Median compared with no OFS (high certainty).
OFS leads to lower disease‐free survival (DFS) Median compared with no OFS (high certainty).
OFS may leads to higher toxicity ‐ hot flushes (a combination of "grade 3/4" and "any grade"… compared with no OFS (low certainty).
OFS may leads to higher toxicity ‐ bone health (osteoporosis defined by a T score < ‐2.5) compared with no OFS (low certainty).
OFS probably leads to lower contralateral breast cancer compared with no OFS (moderate certainty).