Topical antibiotics vs placebo/no treatment
Ear pain (otalgia) or discomfort or local irritation · patients with mucopurulent otorrhoea
1 finding from 1 review
- no estimate extracted1 study · 35 participantsVery low
Findings
What do systematic reviews say?
1,352 questions · 1,400 findings · 169 reviews
No studies found 309 · 22.1%GRADE not reported 115 · 8.2%Very low 350 · 25%Low 324 · 23.1%Moderate 240 · 17.1%High 62 · 4.4%
Topical antibiotics vs placebo/no treatment
Hearing · patients with mucopurulent otorrhoea
1 finding from 1 review
- no estimate extracted1 study · 35 participantsVery low
Topical antibiotics vs placebo/no treatment
Serious complications · patients with mucopurulent otorrhoea
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Topical antibiotics vs placebo/no treatment
Suspected ototoxicity · patients with mucopurulent otorrhoea
1 finding from 1 review
- no estimate extracted1 study · 35 participantsVery low
Topical antibiotics vs acetic acid
Resolution of ear discharge ‐ measured at 1 to 2 weeks · chronic suppurative otitis media
It is very uncertain whether topical antibiotics changes resolution of ear discharge (1 to 2 weeks) Aminoglycosides compared with acetic acid (very low certainty).
1 finding from 1 review
- Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes onlyRR 0.88 [0.72, 1.08]1 study · 100 participantsVery low
Topical antibiotics vs acetic acid
Resolution of ear discharge ‐ measured after 4 weeks · chronic suppurative otitis media
The review found no eligible studies for this question.
1 finding from 1 review
- Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Topical antibiotics vs acetic acid
Quality of life ‐ not measured · chronic suppurative otitis media
The review found no eligible studies for this question.
1 finding from 1 review
- Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Topical antibiotics vs acetic acid
Ear pain (otalgia) or discomfort or local irritation · chronic suppurative otitis media
It is very uncertain whether topical antibiotics changes ear pain, discomfort, irritation compared with acetic acid (very low certainty).
1 finding from 1 review
- Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes onlyRR 0.16 [0.02, 1.34]2 studies · 189 participantsVery low
Topical antibiotics vs acetic acid
Hearing · chronic suppurative otitis media
1 finding from 1 review
- Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes onlyno estimate extracted1 study · 107 participantsVery low
Topical antibiotics vs acetic acid
Serious complications ‐ not measured · chronic suppurative otitis media
The review found no eligible studies for this question.
1 finding from 1 review
- Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Topical antibiotics vs acetic acid
Suspected ototoxicity · chronic suppurative otitis media
It is very uncertain whether topical antibiotics changes suspected ototoxicity compared with acetic acid (very low certainty).
1 finding from 1 review
- Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes onlyno estimate extracted1 study · 100 participantsVery low
Topical antibiotics vs no topical antibiotic.
Surgical site infection · people presenting for surgery where healing of surgical wound planned to be by primary intention
Topical antibiotics probably leads to lower surgical site infection compared with no topical antibiotic. (moderate certainty).
1 finding from 1 review
- Topical antibiotics for preventing surgical site infection in wounds healing by primary intention 2016 · Cochrane Headline outcomes onlyRR 0.61 [0.42, 0.87]7 studies · 5427 participantsModerate
Topical antibiotics vs antiseptic agent
Number of wounds healed · people presenting for surgery where healing of surgical wound planned to be by primary intention
The review found no eligible studies for this question.
1 finding from 1 review
- Topical antibiotics for preventing surgical site infection in wounds healing by primary intention 2016 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Topical antibiotics vs no topical antibiotic.
Allergic contact dermatitis · people presenting for surgery where healing of surgical wound planned to be by primary intention
It is very uncertain whether topical antibiotics changes allergic contact dermatitis compared with no topical antibiotic. (very low certainty).
1 finding from 1 review
- Topical antibiotics for preventing surgical site infection in wounds healing by primary intention 2016 · Cochrane Headline outcomes onlyRR 3.94 [0.46, 34]3 studies · 3012 participantsVery low
Topical antibiotics vs no topical antibiotic.
Adverse event: anaphylaxis · people presenting for surgery where healing of surgical wound planned to be by primary intention
The review found no eligible studies for this question.
1 finding from 1 review
- Topical antibiotics for preventing surgical site infection in wounds healing by primary intention 2016 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Topical antibiotics vs no topical antibiotic.
Antibiotic resistance · people presenting for surgery where healing of surgical wound planned to be by primary intention
The review found no eligible studies for this question.
1 finding from 1 review
- Topical antibiotics for preventing surgical site infection in wounds healing by primary intention 2016 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Topical antibiotics vs no topical antibiotic.
Number of wounds healed · people presenting for surgery where healing of surgical wound planned to be by primary intention
The review found no eligible studies for this question.
1 finding from 1 review
- Topical antibiotics for preventing surgical site infection in wounds healing by primary intention 2016 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Topical antibiotics vs antiseptic agent
Surgical site infection · people presenting for surgery where healing of surgical wound planned to be by primary intention
Topical antibiotics probably leads to lower surgical site infection compared with antiseptic (moderate certainty).
1 finding from 1 review
- Topical antibiotics for preventing surgical site infection in wounds healing by primary intention 2016 · Cochrane Headline outcomes onlyRR 0.49 [0.3, 0.8]4 studies · 1299 participantsModerate
Topical antibiotics vs antiseptic agent
Allergic contact dermatitis · people presenting for surgery where healing of surgical wound planned to be by primary intention
It is very uncertain whether topical antibiotics changes allergic contact dermatitis compared with antiseptic (very low certainty).
1 finding from 1 review
- Topical antibiotics for preventing surgical site infection in wounds healing by primary intention 2016 · Cochrane Headline outcomes onlyRR 0.97 [0.52, 1.82]1 study · 541 participantsVery low
Topical antibiotics vs antiseptic agent
Adverse event: anaphylaxis · people presenting for surgery where healing of surgical wound planned to be by primary intention
The review found no eligible studies for this question.
1 finding from 1 review
- Topical antibiotics for preventing surgical site infection in wounds healing by primary intention 2016 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found