Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,776 questions · 7,311 findings · 959 reviews · Headline outcomes only

No studies found 1,498 · 20.5%GRADE not reported 303 · 4.1%Very low 1,839 · 25.2%Low 1,991 · 27.2%Moderate 1,277 · 17.5%High 403 · 5.5%

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Summary of findings: high‐dose urate oxidase vs low‐dose urate oxidase

Serum urate normalisation ‐ not reported · children with haematological malignancy at risk of tumour lysis syndrome

Summary of findings: high‐dose urate oxidase showed no clear difference in normalisation of serum uric acid ( compared with low‐dose urate oxidase (low certainty).

1 finding from 1 review

Summary of findings: high‐dose urate oxidase vs low‐dose urate oxidase

Frequency of adverse events ( · children with haematological malignancy at risk of tumour lysis syndrome

Summary of findings: high‐dose urate oxidase showed no clear difference in frequency of adverse events ( compared with low‐dose urate oxidase (low certainty).

1 finding from 1 review

Foley catheter vs intravenous (IV) oxytocin

Vaginal delivery not achieved within 24 hours · pregnant women with a previous low transverse caesarean section, singleton live pregnancy with cephalic presentation, period of gestation…

Foley catheter showed no clear difference in vaginal delivery not achieved within 24 hours compared with intravenous (IV) oxytocin (low certainty).

1 finding from 1 review

Foley catheter vs intravenous (IV) oxytocin

Uterine hyperstimulation with fetal heart rate changes · pregnant women with a previous low transverse caesarean section, singleton live pregnancy with cephalic presentation, period of gestation…

Foley catheter showed no clear difference in uterine hyperstimulation with fetal heart rate changes compared with intravenous (IV) oxytocin (low certainty).

1 finding from 1 review