Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,749 questions · 14,261 findings · 832 reviews

No studies found 3,655 · 25.6%GRADE not reported 2,111 · 14.8%Very low 3,646 · 25.6%Low 3,028 · 21.2%Moderate 1,501 · 10.5%High 320 · 2.2%

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Herbal mouthrinse vs Chlorhexidine 0.2% mouthrinse

Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)

Herbal mouthrinse showed no clear difference in presence of dry socket compared with chlorhexidine 0.2% mouthrinse; GRADE not reported.

1 finding from 1 review

Autologous platelet‐rich plasma vs placebo or no treatment

Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)

It is very uncertain whether platelet rich plasma changes presence of dry socket compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Artemisia desertorum spreng (Yunnan) vs placebo

Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)

Artemisia desertorum spreng (Yunnan) showed no clear difference in presence of dry socket compared with placebo; GRADE not reported.

1 finding from 1 review

Chlorhexidine 0.2% socket irrigation (monoject syringe) vs Chlorhexidine 0.2% mouthrinse

Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)

Chlorhexidine 0.2% socket irrigation (monoject syringe) led to lower presence of dry socket compared with chlorhexidine 0.2% mouthrinse; GRADE not reported.

1 finding from 1 review

Primary closure of the extraction socket with a mucoperiosteal flap vs Application of platelet-rich fibrin (PRF) without primary closure

Complications and side effects · People on antiresorptive treatment undergoing tooth extraction (at risk of MRONJ)
1 finding from 1 review