Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,534 questions · 5,247 findings · 456 reviews

No studies found 1,142 · 21.8%GRADE not reported 1,503 · 28.6%Very low 1,040 · 19.8%Low 869 · 16.6%Moderate 554 · 10.6%High 139 · 2.6%

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Ty21a vaccine (three doses) vs control

Cases of typhoid fever, Year 3 · adults and children aged 5 years of age and older

Ty21a vaccine (three doses) probably leads to lower cases of typhoid fever, Year 3 compared with control (moderate certainty).

1 finding from 1 review

Vi polysaccharide vaccine (1 dose) vs control

Incidence of typhoid fever – year 1 Blood culture · adults and children of 2 years of age and older

Vi polysaccharide vaccine (1 dose) leads to lower incidence of typhoid fever – year 1 Blood culture compared with control (high certainty).

1 finding from 1 review

Vi polysaccharide vaccine (1 dose) vs control

Incidence of typhoid fever – year 2 · adults and children of 2 years of age and older

Vi polysaccharide vaccine (1 dose) probably leads to lower incidence of typhoid fever – year 2 compared with control (moderate certainty).

1 finding from 1 review