What do systematic reviews say?

Summary of findings: levofloxacin for inhalation solution vs tobramycin

• Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 282 participants
  High

Summary of findings: levofloxacin for inhalation solution vs tobramycin

• Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 282 participants
  High

Summary of findings: levofloxacin for inhalation solution vs tobramycin

Summary of findings: levofloxacin for inhalation solution leads to lower pulmonary exacerbations: number of hospitalisations due to… compared with tobramycin (high certainty).

• Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis 2022 · Cochrane Headline outcomes only
  RR 0.62 [0.4, 0.98]
  1 study · 282 participants
  High

Summary of findings: levofloxacin for inhalation solution vs tobramycin

• Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 282 participants
  Low

Summary of findings: levofloxacin for inhalation solution vs tobramycin

The review found no eligible studies for this question.

• Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings: levofloxacin for inhalation solution vs tobramycin

• Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 282 participants
  High

Summary of findings: levofloxacin for inhalation solution vs tobramycin

• Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 282 participants
  High

Summary of findings: integrated community case management vs usual facility services

It is very uncertain whether summary of findings: integrated community case management changes any iCCM illness compared with usual facility services (very low certainty).

• Integrated community case management of childhood illness in low‐ and middle‐income countries 2021 · Cochrane Headline outcomes only
  RR 0.96 [0.77, 1.19]
  5898 participants
  Very low

Summary of findings: integrated community case management vs usual facility services plus CCM

• Integrated community case management of childhood illness in low‐ and middle‐income countries 2021 · Cochrane Headline outcomes only
  no estimate extracted
  4 participants
  GRADE not reported

Summary of findings: integrated community case management vs usual facility services plus CCM

• Integrated community case management of childhood illness in low‐ and middle‐income countries 2021 · Cochrane Headline outcomes only
  no estimate extracted
  5 participants
  GRADE not reported

Summary of findings: integrated community case management vs usual facility services

• Integrated community case management of childhood illness in low‐ and middle‐income countries 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 participants
  GRADE not reported

Summary of findings: integrated community case management vs usual facility services

• Integrated community case management of childhood illness in low‐ and middle‐income countries 2021 · Cochrane Headline outcomes only
  no estimate extracted
  4 participants
  GRADE not reported

Summary of findings: integrated community case management vs usual facility services

Summary of findings: integrated community case management showed no clear difference in neonatal mortality rate compared with usual facility services (low certainty).

• Integrated community case management of childhood illness in low‐ and middle‐income countries 2021 · Cochrane Headline outcomes only
  HR 1.01 [0.77, 1.33]
  65209 participants
  Low

Summary of findings: integrated community case management vs usual facility services

It is very uncertain whether summary of findings: integrated community case management changes infant mortality rate compared with usual facility services (very low certainty).

• Integrated community case management of childhood illness in low‐ and middle‐income countries 2021 · Cochrane Headline outcomes only
  HR 0.98 [0.72, 1.34]
  65209 participants
  Very low

Summary of findings: integrated community case management vs usual facility services

• Integrated community case management of childhood illness in low‐ and middle‐income countries 2021 · Cochrane Headline outcomes only
  1.16 [0.99, 1.36]
  4729 participants
  Very low

Summary of findings: integrated community case management vs usual facility services

• Integrated community case management of childhood illness in low‐ and middle‐income countries 2021 · Cochrane Headline outcomes only
  no estimate extracted
  5 participants
  GRADE not reported

Summary of findings: integrated community case management vs usual facility services plus CCM

It is very uncertain whether summary of findings: integrated community case management changes any iCCM illness compared with usual facility services plus CCM (very low certainty).

• Integrated community case management of childhood illness in low‐ and middle‐income countries 2021 · Cochrane Headline outcomes only
  RR 1.59 [0.66, 3.87]
  7876 participants
  Very low

Summary of findings: integrated community case management vs usual facility services plus CCM

• Integrated community case management of childhood illness in low‐ and middle‐income countries 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 participants
  GRADE not reported

Summary of findings. Surgery (percutaneous wire fixation) vs not surgery (cast only)

The review found no eligible studies for this question.

• Interventions for treating wrist fractures in children 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found
• Interventions for treating wrist fractures in children 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 123 participants
  Low

Summary of findings. Surgery (percutaneous wire fixation) vs not surgery (cast only)

It is very uncertain whether summary of findings. Surgery (percutaneous wire fixation) changes 'Treatment failure': various secondary procedures such as… compared with not surgery (cast only) (very low certainty).

• Interventions for treating wrist fractures in children 2018 · Cochrane Headline outcomes only
  RR 0.52 [0.33, 0.83]
  4 studies · 253 participants
  Very low