Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,584 questions · 3,695 findings · 567 reviews

No studies found 784 · 21.2%GRADE not reported 308 · 8.3%Very low 1,036 · 28%Low 971 · 26.3%Moderate 440 · 11.9%High 156 · 4.2%

Intervention not reported

Incidence of AAD · Children receiving antibiotic treatment between 4 and 28 days duration for a variety of infections

The intervention probably leads to lower incidence of AAD (moderate certainty).

1 finding from 1 review

Intervention not reported

Incidence of AAD: Probiotic dose (≥5 billion CFUs of probiotics/day) · Children receiving antibiotic treatment between 4 and 28 days duration for a variety of infections

The intervention probably leads to lower incidence of AAD: Probiotic dose (≥5 billion CFUs of probiotics/day) (moderate certainty).

1 finding from 1 review

Intervention not reported

Adverse events · Children receiving antibiotic treatment between 4 and 28 days duration for a variety of infections

The intervention showed no clear difference in adverse events (low certainty).

1 finding from 1 review

Intervention not reported

Tardive dyskinesia: Not improved to a clinically important extent · patients with antipsychotic‐induced TD

The intervention may leads to lower tardive dyskinesia: Not improved to a clinically important extent (low certainty).

1 finding from 1 review

Intervention not reported

Tardive dyskinesia: Deterioration of symptoms · patients with antipsychotic‐induced TD

It is very uncertain whether the intervention changes tardive dyskinesia: Deterioration of symptoms (very low certainty).

1 finding from 1 review

Intervention not reported

Acceptability of treatment: Leaving the study early · patients with antipsychotic‐induced TD

It is very uncertain whether the intervention changes acceptability of treatment: Leaving the study early (very low certainty).

1 finding from 1 review

Intervention not reported

Social confidence, social inclusion, social networks, or personalised quality of life measures · patients with antipsychotic‐induced TD

The review found no eligible studies for this question.

1 finding from 1 review

Surgical portosystemic shunts vs transjugular intrahepatic portosystemic shunt (TIPS)

All‐cause mortality at 30 days · people with cirrhotic portal hypertension

It is very uncertain whether surgical portosystemic shunts changes all‐cause mortality at 30 days compared with transjugular intrahepatic portosystemic shunt (TIPS) (very low certainty).

1 finding from 1 review

Surgical portosystemic shunts vs transjugular intrahepatic portosystemic shunt (TIPS)

All‐cause mortality at 5 years · people with cirrhotic portal hypertension

It is very uncertain whether surgical portosystemic shunts changes all‐cause mortality at 5 years compared with transjugular intrahepatic portosystemic shunt (TIPS) (very low certainty).

1 finding from 1 review

Surgical portosystemic shunts vs transjugular intrahepatic portosystemic shunt (TIPS)

Reintervention Number of women with reintervention · people with cirrhotic portal hypertension

It is very uncertain whether surgical portosystemic shunts changes number of participants with reintervention at 5 years compared with transjugular intrahepatic portosystemic shunt (TIPS) (very low certainty).

1 finding from 1 review

Surgical portosystemic shunts vs transjugular intrahepatic portosystemic shunt (TIPS)

Irreversible shunt occlusion at 5 years · people with cirrhotic portal hypertension

It is very uncertain whether surgical portosystemic shunts changes irreversible shunt occlusion at 5 years compared with transjugular intrahepatic portosystemic shunt (TIPS) (very low certainty).

1 finding from 1 review