Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,372 questions · 3,874 findings · 666 reviews

No studies found 431 · 11.1%GRADE not reported 783 · 20.2%Very low 995 · 25.7%Low 909 · 23.5%Moderate 596 · 15.4%High 160 · 4.1%

Summary of findings: complete control of vomiting during the overall phase (MEC) when vs treatment with granisetron

Interventions (corticosteroids included in all regimens)a · adult cancer patients at risk for CINV caused by moderately emetogenic chemotherapy

The review found no eligible studies for this question.

1 finding from 1 review

Summary of findings: serious adverse events (MEC) when vs treatment with granisetron

Interventions (corticosteroids included in all regimens)a · adult cancer patients at risk for CINV caused by moderately emetogenic chemotherapy

The review found no eligible studies for this question.

1 finding from 1 review

1-19 remaining teeth vs 20-32 remaining teeth

Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies

In prospective cohorts, adults with 1-19 teeth had a higher cumulative incidence of ACVD-related events than adults with 20-32 teeth (RR 1.69, 95% CI 1.13 to 2.53; 2 cohort studies, I2=60%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).

1 finding from 1 review

Edentulous (0 remaining teeth) vs 20-32 remaining teeth

All-cause mortality (ACM) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies

In prospective cohorts, edentulous adults (0 teeth) had a higher cumulative incidence of all-cause mortality than adults with 20-32 teeth (RR 2.27, 95% CI 1.82 to 2.83; 8 cohort studies, I2=94%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).

1 finding from 1 review

0-10 remaining teeth vs 25-32 remaining teeth

Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies

In prospective cohorts, adults with 0-10 teeth had a higher cumulative incidence of ACVD-related events than adults with 25-32 teeth (RR 2.65, 95% CI 1.84 to 3.81; 4 cohort studies, I2=87%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).

1 finding from 1 review